Advances in 3D Printing for Pharmaceutical Sciences: Applications, Barriers, and Future Directions

Ujwala Shivaji , Smita Pimple , Aditya Bhosle , Shivam Yadav

3D printing; Additive manufacturing; Personalized medicine; Drug delivery systems; Regulatory challenges

Three-dimensional (3D) printing, also known as additive manufacturing and introduced in the 1980s, has significantly transformed the pharmaceutical industry by enabling efficient, cost-effective production of complex and patient-specific dosage forms. In pharmaceutics, 3D printing facilitates the development of personalized medicines, polypills, and controlled drug delivery systems, offering advantages such as precise dosing, enhanced drug loading, design flexibility, and reduced material waste, making it particularly valuable for pediatric, geriatric, and orphan drug therapies. Various techniques including fused deposition modeling (FDM), stereolithography (SLA), binder jetting, and semi-solid extrusion are used to fabricate oral, transdermal, and implantable dosage forms, while emerging approaches like bioprinting and 4D printing are opening new possibilities for responsive and advanced therapeutic systems. Despite its strong potential, widespread commercial adoption remains limited due to challenges related to process reproducibility, material compatibility, scalability, and regulatory compliance, indicating that further technological refinement and regulatory clarity are essential to fully realize the promise of 3D printing in personalized and precise medicine.

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"Advances in 3D Printing for Pharmaceutical Sciences: Applications, Barriers, and Future Directions", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.11, Issue 1, page no.b536-b558, January-2026, Available :https://ijsdr.org/papers/IJSDR2601169.pdf

Volume 11 Issue 1, January-2026

Pages : b536-b558

Paper Reg. ID: IJSDR_307079

Published Paper Id: IJSDR2601169

Downloads: 000192

Research Area: Pharmacy All

Country: Pune, Maharashtra, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2601169

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2601169

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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