Guillain-Barré Syndrome: The Silent Predator That Paralyzes — Mechanisms, Challenges, and Clinical Realities”

Mr. Bharat Vidhate , Neha Harish Bansode , Aniket Bhuraram Kumavat , Ankit Subhash Gautam , Girish Yogesh Patil

Guillain–Barré syndrome (GBS) is a rare, but potentially fatal, immune-mediated disease of the peripheral nerves and nerve roots that is usually triggered by infections. The incidence of GBS can therefore increase during outbreaks of infectious diseases, as was seen during the Zika virus epidemics in 2013 in French Polynesia and 2015 in Latin America. Diagnosis and management of GBS can be complicated as its clinical presentation and disease course are heterogeneous, and no international clinical guidelines are currently available. To support clinicians, especially in the context of an outbreak, we have developed a globally applicable guideline for the diagnosis and management of GBS. The guideline is based on current literature and expert consensus, and has a ten-step structure to facilitate its use in clinical practice. We first provide an introduction to the diagnostic criteria, clinical variants and differential diagnoses of GBS. The ten steps then cover early recognition and diagnosis of GBS, admission to the intensive care unit, treatment indication and selection, monitoring and treatment of disease progression, prediction of clinical course and outcome, and management of complications and sequence.

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"Guillain-Barré Syndrome: The Silent Predator That Paralyzes — Mechanisms, Challenges, and Clinical Realities”", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.11, Issue 1, page no.a185-a190, January-2026, Available :https://ijsdr.org/papers/IJSDR2601023.pdf

Volume 11 Issue 1, January-2026

Pages : a185-a190

Paper Reg. ID: IJSDR_306761

Published Paper Id: IJSDR2601023

Downloads: 000238

Research Area: Pharmacy All

Country: Kalyan east, Maharashtra, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2601023

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2601023

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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