FORMULATION AND EVALUATION OF RIVAROXABAN TRANSDERMAL PATCH
T. Gayathri
, K. Nishith , B. Udayteja , A. Pavithra , S. Pravalika,R. Archana
Rivaroxaban, HPMC, Solvent casting, Transdermal drug delivery system, Sustained release.
The present study focuses on the formulation and Evaluation of a Rivaroxaban Transdermal Patch designed for controlled and localized drug delivery through the skin. Transdermal drug delivery system offers several advantages, including avoidance of first-pass metabolism, improved patient compliance, and steady drug release over extended periods. Rivaroxaban was used as the model drug, with HPMC as the polymer, PEG 600 as the plasticizer, and IPA as the solvent. Patches were prepared by the solvent casting method and evaluated for parameters like thickness, drug content, folding endurance, and in vitro drug release. The results showed uniformity and sustained drug release, indicating that the patch is suitable for effective transdermal delivery.
"FORMULATION AND EVALUATION OF RIVAROXABAN TRANSDERMAL PATCH", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.10, Issue 7, page no.a878-a894, July-2025, Available :https://ijsdr.org/papers/IJSDR2507100.pdf
Volume 10
Issue 7,
July-2025
Pages : a878-a894
Paper Reg. ID: IJSDR_304123
Published Paper Id: IJSDR2507100
Downloads: 000435
Research Area: Science and Technology
Country: -, -, India
DOI: https://doi.org/10.56975/ijsdr.v10i7.304123
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
