Synthesis, Characterization, and Antimicrobial Activity Evaluation of Some Newly Synthesized Benzothiazole Derivatives by Azo Coupling Reaction

Rima Mahapatra , SK Jamal Siddique , MD Rais Ahamed , Chiranjit Mandal

Benzothiazole, Diazotization, Coupling, Antimicrobial

Benzothiazole is the most commonly used lead compound for drug discovery and development due to its numerous pharmacological activities. We have synthesized some novel benzothiazole derivatives by diazotization and coupling reaction between our lead compound 2-aminobenzothiazole, and different substituted phenols or anilines. Synthesized compounds were purified by recrystallization and then characterized by melting point determination and IR spectroscopy. After biological evaluation, some of those synthesized compounds show effective antimicrobial activity against gram-negative and gram-positive bacterial strains. After this research work, we want to emphasize the area where azo compounds are produced by diazotization and coupling reactions are not only used as dyes but also may have a wide range of pharmacological activity if it is a benzothiazole derivatives.

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"Synthesis, Characterization, and Antimicrobial Activity Evaluation of Some Newly Synthesized Benzothiazole Derivatives by Azo Coupling Reaction", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.10, Issue 6, page no.b306-b313, June-2025, Available :https://ijsdr.org/papers/IJSDR2506135.pdf

Volume 10 Issue 6, June-2025

Pages : b306-b313

Paper Reg. ID: IJSDR_303602

Published Paper Id: IJSDR2506135

Downloads: 000464

Research Area: Chemistry All

Country: Howrah, West Bengal, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2506135

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2506135

DOI: https://doi.org/10.56975/ijsdr.v10i6.303602

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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