Personalized medicine: A novel approach to chronic obstructive pulmonary disease treatment
Kshitij Patel
, Nistha Rai
SERPINA1, Smoking, Chronic bronchitis, Biomarkers, COPD, personalized medicines etc
COPD is a long-standing and multifactorial respiratory disease brought on mainly by chronic bronchitis and emphysema and constitutes a substantial global burden of morbidity and mortality, especially in LMICs (low- and middle-income countries). Advances in research have revealed the multifactorial nature of COPD, driven by genetic predisposition, environmental exposures, and lifestyle factors. Key molecular biomarkers, including C-reactive protein and malondialdehyde, have improved diagnostic and prognostic capabilities. Genetic insights, such as SERPINA1 mutations and telomerase deficiencies, have deepened the understanding of its pathogenesis, highlighting the potential of precision medicine. Innovations in imaging techniques like computed tomography and quantitative imaging have facilitated the classification of COPD subtypes, enabling the development of targeted therapies such as monoclonal antibodies and phosphodiesterase-4 inhibitors. However, challenges like disease heterogeneity, limited pharmacogenomic applications, and insufficient clinical trial models persist. Emerging technologies, including multi-omics and systems pharmacology, offer promising pathways for personalized treatment. Future studies focus on incorporating these innovations into clinical settings and overcoming current challenges to ensure holistic COPD management and better patient outcomes. Collaboration between researchers and healthcare professionals will play a crucial role in developing advanced treatments and enhancing the quality of life for those living with COPD.
"Personalized medicine: A novel approach to chronic obstructive pulmonary disease treatment", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.10, Issue 3, page no.c404-c423, March-2025, Available :https://ijsdr.org/papers/IJSDR2503251.pdf
Volume 10
Issue 3,
March-2025
Pages : c404-c423
Paper Reg. ID: IJSDR_301360
Published Paper Id: IJSDR2503251
Downloads: 000205
Research Area: Humanities All
Country: Lucknow, Uttar Pradesh, India
DOI: https://doi.org/10.56975/ijsdr.v10i3.301360
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
