Various Topical Formulations of Salicylic Acid in Market: An Overview

Greeshma Surendran , Aditya Sharma , Chinmay Patil , Sanjana Mhatre , Khushi Kakde

Salicylic acid, Acne vulgaris, Formulations, Antibacterial agent, Keratolytic, Tretinoin

Salicylic acid (SA) comes from birch leaves and white willow bark, has become an important ingredient in both industrial and medical uses. The article examines the many functions of salicylic acid, with a focus on dermatological therapies for diseases including molluscum contagiosum, psoriasis, and acne vulgaris. SA is an effective keratolytic and antibacterial agent that can exfoliate skin, lower inflammation, and improve the absorption of other topical therapies. The relative efficacy of tretinoin and SA was evaluated in a randomized control trial, which showed comparable results with tretinoin responding more quickly. With a focus on its safety profile and possible adverse effects, the study also explores the chemistry of salicylic acid, its derivatives, and several topical forms. To further comprehend salicylic acid's pharmacokinetics, its absorption, distribution, metabolism, and elimination (ADME) are examined. Different formulations—such as gels, lotions, and shampoos—are examined in relation to their uses and therapeutic advantages. In its conclusion, this study highlights the significance of salicylic acid in modern dermatological treatment while outlining potential directions for further investigation to improve formulation effectiveness and patient safety.

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"Various Topical Formulations of Salicylic Acid in Market: An Overview ", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 12, page no.a79-a88, December-2024, Available :https://ijsdr.org/papers/IJSDR2412012.pdf

Volume 9 Issue 12, December-2024

Pages : a79-a88

Paper Reg. ID: IJSDR_212729

Published Paper Id: IJSDR2412012

Downloads: 000347329

Research Area: Science & Technology

Country: Navi Mumbai/Raigad, Maharashtra, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2412012

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2412012

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition