An observational study on correlation of Non-Alcoholic Fatty Liver Disease with various components of metabolic syndrome
Dr Abhishek Saklani
, Dr Kulkarni Shashwat , Dr. Sidhartha yadav , Dr Mohar Singh Uchariya , Dr Kumar Siddharth, Dr. Manju Pandey
Non-Alcoholic Fatty Liver Disease; Metabolic Syndrome; Insulin Resistance; Western Uttar Pradesh; Obesity; Type 2 Diabetes
Non-Alcoholic Fatty Liver Disease (NAFLD) is a common hepatic manifestation linked with Metabolic Syndrome (MetS), a cluster of metabolic abnormalities including insulin resistance, obesity, dyslipidemia, and hypertension, which increases cardiovascular risk. The prevalence of NAFLD is rising in India, notably in populations with high rates of MetS and type 2 diabetes mellitus (T2DM). This study aims to explore the correlation between NAFLD and MetS components in patients from Western Uttar Pradesh, a region with a significant diabetic population. The objective was to evaluate the prevalence and characteristics of NAFLD in relation to MetS among patients in a tertiary care hospital setting. Methods: This cross-sectional study involved 127 NAFLD patients aged 18 and above, attending the outpatient or inpatient department at a tertiary care center from October 2022 to July 2023. MetS was diagnosed based on NCEP ATP III criteria, and NAFLD was confirmed via ultrasonography. Patients with chronic alcohol intake, viral hepatitis, or other liver diseases were excluded. Results: NAFLD prevalence was higher in females (57.48%) than males (42.52%), with the highest occurrence among those aged 50-60. A significant association was observed between NAFLD and MetS, particularly in patients with elevated BMI, waist circumference, fasting blood sugar, and triglycerides. Patients with MetS presented more severe NAFLD grades compared to those without MetS. Conclusion: The study underscores the need for early metabolic screening in NAFLD patients to prevent severe liver and cardiovascular complications. The findings highlight a high prevalence of NAFLD among females and support the association between NAFLD severity and MetS components, advocating for targeted interventions to manage metabolic health in this region.
"An observational study on correlation of Non-Alcoholic Fatty Liver Disease with various components of metabolic syndrome ", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 11, page no.639 - 646, December-2024, Available :https://ijsdr.org/papers/IJSDR2411075.pdf
Volume 9
Issue 11,
December-2024
Pages : 639 - 646
Paper Reg. ID: IJSDR_212736
Published Paper Id: IJSDR2411075
Downloads: 000347157
Research Area: Medical Science
Country: MATHURA, UTTAR PRADESH, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
