Implications of Postbiotic on Hepatotoxicity

Taniya , Sachin Kumar Sharma , Divya Katoch , Saurav Anand , Ramica Sharma

Postbiotics, Hepatotoxicity, Hepatoprotection, Antioxidant properties, Inflammatory pathways, Gut-liver axis, Probiotics vs postbiotics

The recent development of postbiotics, pronoun to be a non-viable bacterial substance or a metabolite produced by live probiotic microorganisms has introduced new dimensions to the researchers in the field of hepatoprotection. This review explores the effects postbiotics have on hepatotoxicity, which is defined as any damage done to the liver or its parts by a drug or substance that affects it negatively. Nevertheless, they are a more stable and safer option than probiotics; these products can be consumed without health consequences associated with using live bacteria. The antioxidant and gut-liver axis modulation as well as inflammation process explains how postbiotics cause hepatoprotective actions in various ways. This relationship is built on many advantages that postbiotics have over probiotics such as efficiency, safety among others. Lastly, it presents a brief description of possible therapeutics related to dietary supplementation and pharmacological strategies using postbiotics with suggestions for future research streams within this area of study. The findings provide evidence for the therapeutic role of postbiotics as preventive agents against hepatotoxicity as well as the agents that potentiate liver function.

Published Paper   E-Certificate

"Implications of Postbiotic on Hepatotoxicity", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 11, page no.632 - 638, November-2024, Available :https://ijsdr.org/papers/IJSDR2411074.pdf

Volume 9 Issue 11, November-2024

Pages : 632 - 638

Paper Reg. ID: IJSDR_212784

Published Paper Id: IJSDR2411074

Downloads: 000347152

Research Area: Pharmacy

Country: mohali, Punjab, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2411074

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2411074

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition