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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Lepidagathis keralensis: Pharmacognostical, Phytochemical, and Pharmacological Investigations for Therapeutic Applications |
| Authors Name: | Sarika PV , Celestin baboo R V , Sirajudheen M K |
| Unique Id: | IJSDR2409004 |
| Published In: | Volume 9 Issue 9, September-2024 |
| Abstract: | ABSTRACT This paper describes the Pharmacognostical and Phytochemical screening of selected plants are Lepidagathis keralensis. Lepidagathis keralensis is a plant belonging to the family Acanthaceae commonly called as ‘Paramullu’.This review paper discusses in detail study of Pharmacognostical, Phytochemical and In vitro cytotoxicity screening of Lepidagathis keralensis . In Pharmacognostical study discusses the Macroscopy and Microscopy of selected plant. Here the Macroscopical study describe the characters like colour, odour, taste, size, shape. The Microscopical study describe the fresh leaves, Stem and Root were subjected to various anatomical studies. The sections of leaf,stem and root specimens were taken using sharp blade and stained with various staining reagents like phloroglucinol-HCL, iodine, safranin and observed under microscope.Phytochemical screening of Lepidagathis keralensis shows the presence of alkaloid, flavonoid and Phenol. Rf value of Lepidagathis keralensis crude extract was determined by thin layer chromatography and it was 0.40. Cytotoxicity screening of Lepidagathis keralensis was done by MTT assay method.The sample was found to cause significant reduction in cell viability of normal fibroblast cells at highest concentration. Since no significant reduction was observed in lower concentrations, test samples can be considered as non-cytotoxic to normal cells at lower concentrations. |
| Keywords: | Keywords: Lepidagathis keralensis, Microscopy, Macroscopy, Phytochemical screening,Alkaloid,Flavonoid, Phenol, Cytotoxicity. |
| Cite Article: | "Lepidagathis keralensis: Pharmacognostical, Phytochemical, and Pharmacological Investigations for Therapeutic Applications", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 9, page no.20 - 34, September-2024, Available :http://www.ijsdr.org/papers/IJSDR2409004.pdf |
| Downloads: | 00031 |
| Publication Details: | Published Paper ID: IJSDR2409004 Registration ID:212421 Published In: Volume 9 Issue 9, September-2024 DOI (Digital Object Identifier): Page No: 20 - 34 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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