A Review: Microwave Assisted Synthesis and Characterization of Some novel 3, 5-diaryl-2-pyrazolin-1-Carboxaldehyde Hydrazones.
Alzheimer's; Hydrazones; biologic activity; cancer; guanylhydrazones; Azomethine.
Hydrazones and their derivatives are very important compounds in medicinal chemistry1 due to their reported biological activity for the treatment of several diseases, like Alzheimer's, cancer, inflammation, and leishmaniasis. However, most of the investigations on hydrazones available in literature today are directed to the synthesis of these molecules with little discussion available on their biological activities. With the purpose of bringing lights into this issue, we performed a revision of the literature and wrote this review based on some of the most current research reports of hydrazones and derivatives, making it clear that the synthesis of these molecules can lead to new drug prototypes. Our goal is to encourage more studies focused on the synthesis and evaluation of new hydrazones, as a contribution to the development of potential new drugs for the treatment of various diseases. The development of novel compounds, hydrazones has shown that they possess a wide variety of biological activities viz. antimicrobial, anticonvulsant, antidepressant, anti-inflammatory2, analgesic, antiplatelet, antimalarial, anticancer3, antifungal, antitubercular, antiviral, cardio protective etc., Hydrazones/azomethines/imines possess-NHN = CH- and constitute an important class of compounds for new drug development. A number of researchers have synthesized and evaluated the biological activities4 of hydrazones. This review aims at highlighting the diverse biological activities of hydrazones.
"A Review: Microwave Assisted Synthesis and Characterization of Some novel 3, 5-diaryl-2-pyrazolin-1-Carboxaldehyde Hydrazones.", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 7, page no.1059 - 1067, July-2024, Available :https://ijsdr.org/papers/IJSDR2407122.pdf
Volume 9
Issue 7,
July-2024
Pages : 1059 - 1067
Paper Reg. ID: IJSDR_212178
Published Paper Id: IJSDR2407122
Downloads: 000347233
Research Area: Chemistry
Country: Chittorgarh, Rajasthan, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
