A Review About Selenium, An Essential Micronutrient
Selenium (Se), which is integrated into selenoproteins, is present in high concentrations in the thyroid gland. Se is regarded by the scientific community as a subject of rising interest. Schwarz was curious about the liver necrosis that occurs in lab rats that consume a torula yeast-containing diet. The issue was solved by switching from torula yeast to Saccharomyces yeast. Schwarz was able to use this experience to demonstrate the selenium deficiency of torula and to discover the first disease that was selenium responsive. Different investigational sequences are needed for common thyroid disorder such hypothyroidism, hyperthyroidism, and thyroid nodules in order to help with creating a diagnosis and treatment strategy. Women of childbearing age frequently experience thyroid issues, which call for a specialised treatment plan. Understanding uncommon thyroid diseases enables individualised workups in these situations. In the 1970s, plasma Se levels ranged from 0.63 to 0.76 mmol/L, which was among the lowest values ever recorded worldwide due to the poor dietary intake of selenium (25 mcg/day). The plasma selenium concentrations have grown by 70% as a result of the addition of selenium to fertilisers. A significant symptom of autoimmune hyperthyroidism, which frequently affects people with Graves' illness, is Graves' orbitopathy (GO). The thyroid gland expresses the majority of the known selenoproteins. Selenium shortage results in a decrease in these enzymes' expression and activity, which raises T4 levels while lowering T3 levels. The most prevalent types of autoimmune thyroid illness are Graves' disease and Hashimoto thyroid. More than 1% to 2% of the world's population is affected by AITD, which is often diagnosed in women between the ages of 30 and 50.
"A Review About Selenium, An Essential Micronutrient ", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 6, page no.778 - 782, June-2024, Available :https://ijsdr.org/papers/IJSDR2406090.pdf
Volume 9
Issue 6,
June-2024
Pages : 778 - 782
Paper Reg. ID: IJSDR_205768
Published Paper Id: IJSDR2406090
Downloads: 000347133
Research Area: Pharmacy
Country: Kozhikode, Kerala, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
