PHYTOCHEMICAL EVALUATION AND AMYLASE A GLUCOSIDASE INHIBITORY AND ANTIOXIDANT ACTIVITIES OF URTICA DIOICA SEEDS

M.Manasa

Glucosidase Inhibitory, Antioxidant Activities, Urtica dioica, Seed Extracts

Using different in vitro models such as α-amylase and α-glucosidase inhibitory effects and antioxidant activity, the primary goal of this study is to assess the hypoglycemic activity of Urtica dioica. seeds. The antidiabetic and antioxidant activities were explained by the presence of flavonoids and phenolics, which were discovered through phytochemical screening of fruit and seed extracts. Among the many biological benefits shown by flavonoids—a class of polyphenolic compounds—are anti-inflammatory, antihepatotoxic, antiulcer, antidiabetic, antithrombotic, and more. Additionally, they impede the activity of enzymes like xanthine oxidase and aldose reductase. By comparing UDSP with the standard medicine acarbose, which is a particular inhibitor of α glucosidase, and assessing its α amylase and α glucosidase inhibitory activities, the in vitro antidiabetic efficacy of UDSP was assessed. Additionally, acarbose has an inhibiting effect on α amylase. The quantity of glucose that is generated by the activity of α glucosidase can be approximated by utilizing the enzymes glucosidase and peroxidase in an experimental setting. In contrast to acarbose's inhibitory activity, the extract exhibited significantly less α glucosidase inhibition.

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"PHYTOCHEMICAL EVALUATION AND AMYLASE A GLUCOSIDASE INHIBITORY AND ANTIOXIDANT ACTIVITIES OF URTICA DIOICA SEEDS", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 6, page no.566 - 576, June-2024, Available :https://ijsdr.org/papers/IJSDR2403085.pdf

Volume 9 Issue 6, June-2024

Pages : 566 - 576

Paper Reg. ID: IJSDR_210425

Published Paper Id: IJSDR2403085

Downloads: 000347099

Research Area: Pharmacy

Country: warangal, TELANGANA, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2403085

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2403085

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition