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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | PHYTOCHEMICAL EVALUATION AND AMYLASE A GLUCOSIDASE INHIBITORY AND ANTIOXIDANT ACTIVITIES OF URTICA DIOICA SEEDS |
| Authors Name: | M.Manasa |
| Unique Id: | IJSDR2403085 |
| Published In: | Volume 9 Issue 3, March-2024 |
| Abstract: | Using different in vitro models such as α-amylase and α-glucosidase inhibitory effects and antioxidant activity, the primary goal of this study is to assess the hypoglycemic activity of Urtica dioica. seeds. The antidiabetic and antioxidant activities were explained by the presence of flavonoids and phenolics, which were discovered through phytochemical screening of fruit and seed extracts. Among the many biological benefits shown by flavonoids—a class of polyphenolic compounds—are anti-inflammatory, antihepatotoxic, antiulcer, antidiabetic, antithrombotic, and more. Additionally, they impede the activity of enzymes like xanthine oxidase and aldose reductase. By comparing UDSP with the standard medicine acarbose, which is a particular inhibitor of α glucosidase, and assessing its α amylase and α glucosidase inhibitory activities, the in vitro antidiabetic efficacy of UDSP was assessed. Additionally, acarbose has an inhibiting effect on α amylase. The quantity of glucose that is generated by the activity of α glucosidase can be approximated by utilizing the enzymes glucosidase and peroxidase in an experimental setting. In contrast to acarbose's inhibitory activity, the extract exhibited significantly less α glucosidase inhibition. |
| Keywords: | Glucosidase Inhibitory, Antioxidant Activities, Urtica dioica, Seed Extracts |
| Cite Article: | "PHYTOCHEMICAL EVALUATION AND AMYLASE A GLUCOSIDASE INHIBITORY AND ANTIOXIDANT ACTIVITIES OF URTICA DIOICA SEEDS", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 3, page no.566 - 576, March-2024, Available :http://www.ijsdr.org/papers/IJSDR2403085.pdf |
| Downloads: | 000337362 |
| Publication Details: | Published Paper ID: IJSDR2403085 Registration ID:210425 Published In: Volume 9 Issue 3, March-2024 DOI (Digital Object Identifier): Page No: 566 - 576 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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