A Comprehensive Analysis of Vitiligo’s Epidemiology, Causes, Pathogenesis, and Pharmacotherapy

MR.KAIWALYA SUNIL TARE , MR. DNYANESHWAR VIJAY THAKARE , Mr. GOPAL D. SHIMPI , Mr. SOMNATH. V. PATIL , Mr. ABHISHEK .C. SONAR

vitiligo, Segmental vitiligo, Non-segmental vitiligo, Genetics of Vitiligo, Oxidative Stress, Pathogenesis, skin disorder.

Vitiligo is a pigmentary disorder characterized by the development of white macules due to melanocyte loss. It is prevalent in the US and Europe, with a higher prevalence in women. Half of patients develop the disease before 20 years, raising concerns about associated diseases like thyroid dysfunction, rheumatoid arthritis, diabetes mellitus, and alopecia areata. Generalized vitiligo is the most common clinical presentation, often affecting the face and acral regions. The disease's course is unpredictable, and treatment response varies. Depigmentation can cause severe psychological distress, reduced quality of life, and increased risk of psychiatric morbidity. This two-part series discusses the clinical presentation, histopathologic findings, and various hypotheses for vitiligo’s pathogenesis based on past and current research.

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"A Comprehensive Analysis of Vitiligo’s Epidemiology, Causes, Pathogenesis, and Pharmacotherapy", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 2, page no.337 - 346, February-2024, Available :https://ijsdr.org/papers/IJSDR2402049.pdf

Volume 9 Issue 2, February-2024

Pages : 337 - 346

Paper Reg. ID: IJSDR_210097

Published Paper Id: IJSDR2402049

Downloads: 000347283

Research Area: Pharmacy

Country: JALGAON, MAHARASHTRA, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2402049

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2402049

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition