INDOLE: A MULTIPOTENT NUCLEUS

Shweta Singh , Amita Rana , Mahendra Rana

Indole, 1H-indole, Heterocyclic ring, Anticonvulsant, Antioxidants, Antidiabetic, Anti-inflammatory, Clinical trials.

Indole (1H-indole) is one of the most important heterocyclic rings which offers a privileged scaffold in drug discovery. Indole derivatives have a vast pharmacological significance and provide a huge opportunity for discovering novel drugs with a different mode of action. The indole nucleus has shown its versatility and therapeutic potency in many naturally occurring compounds like alkaloids. In the recent past many studies have been conducted to integrate and explore various therapeutic aspects of this moiety. The indole scaffold found in both natural and synthetic sources is considered to be one of the most promising heterocyclic compounds possessing several biological activities viz. anticonvulsant, antidiabetic, anti-inflammatory, anti-HIV, anticancer, antitubercular, antioxidants, antihypertensive, antimicrobial, antifungal, etc. Indole derivatives have generated larger interest amongst various researchers to discover therapeutic leads to alleviate a large range of human ailments. In the present review, authors have reviewed and interpreted certain aspects and deciphered certain developments in the field of indole derivatives in the biological, chemical, and pharmacological paradigms of drug discovery including a few drug candidates currently under clinical trials

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"INDOLE: A MULTIPOTENT NUCLEUS ", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 9, page no.1038 - 1055, September-2023, Available :https://ijsdr.org/papers/IJSDR2309151.pdf

Volume 8 Issue 9, September-2023

Pages : 1038 - 1055

Paper Reg. ID: IJSDR_208640

Published Paper Id: IJSDR2309151

Downloads: 000347153

Research Area: Pharmacy

Country: NAINITAL, Uttarakhand, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2309151

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2309151

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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