Study of comparison of various quality control test for expired and non-expired medicine
Tamboli Asiya Yusuf
, Waghmare Samruddhi Kishor , Prof. Sole Patil P.P , Dr. Kolhe S.D
Key words: Paracetamol, friability test, weight variation test, hardness test, disintegration test, dissolution test.
Paracetamol is an antipyretic medicine that belongs to the non-steroidal anti-inflammatory drug class. There are some dosage forms on the market under different names that all have the general claim to be bioequivalent. The main purpose of this experiment is to determine the difference between expired and non-expired medicine. To our knowledge, very few of these studies have been conducted on expired drugs. In addition, most of these studies are related to the stable physical and chemical properties of expired drugs, and no studies have been conducted to confirm their efficacy. In this study, Paracetamol 650 mg standard tablets from different companies were selected. Compression parameters (such as weight change, brittleness, hardness, and dissolution profile) may be found in many ways. Evaluation of these limits is done before maturity, after maturity, and every six months for two years from the expiration date to form a basis. At the time of the research, the active ingredients of all drugs were guaranteed intellectual property, indicating that they retained their potency two years after expiration. Antibiotics, determined by the patterns of "radiant heat tail movement" and "acetic acid-induced writhing", were not significantly different in efficacy and per cent protection. This shows that the drug maintains its results. Small difference in time of explosion during expiration compared to the time difference.
"Study of comparison of various quality control test for expired and non-expired medicine", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 9, page no.876 - 880, September-2023, Available :https://ijsdr.org/papers/IJSDR2309125.pdf
Volume 8
Issue 9,
September-2023
Pages : 876 - 880
Paper Reg. ID: IJSDR_208685
Published Paper Id: IJSDR2309125
Downloads: 000347034
Research Area: Pharmacy
Country: Beed, Maharashtra, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
