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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Comparative Pharmacological Assessment of Polyherbal Formulation Immunoboost Tablet and Immunoboost Herbal Extract Capsule |
| Authors Name: | Renu Kaushik , Amrita Singh , Mohd Zafar , Bhanu P. S. Sagar |
| Unique Id: | IJSDR2309121 |
| Published In: | Volume 8 Issue 9, September-2023 |
| Abstract: | In current scenario, more than 500 Immunomodulatory phytoformulations are globally commercial available either online or offline for prophylactic use (food supplements) therapeutic use (immunomodulatory) to strengthen the body immunity. At yet, Immuno Boost Tablet (IBT, NatureFlip) and Immuno Boost Herbal Extract Capsule (IBHEC, Medinutrica) are not scientifically pharmacologically assessed for their immunomodulatory and other pharmacological investigations. So, present investigation was an attempt to investigate pharmacological potential of IBT and IBHEC. IBT showed 94 SPMs in dried aqueous extract / powder of 12 plants (Haritaki, Amla, Baheda, Haldi, Kali Mirch, Pippali, Guduchi, Yastimadhu / Mulethi, Tulsi, Chitrak, Sounth and Manjishta) whereas IBHEC indicated 44 SPMs in dried aqueous extract of 05 medicinal plants (Amla, Tulsi, Giloy, Haldi and Mulethi). On comparison, IBT was found to be more powerful immunomodulatory then IBHEC. Besides, both IBT and IBHEC were found to be non-toxic / non-lethal (no mortality found even at dose of 2000 mg/kg) with wide safety margin (free from side effects / lethal toxicity). Further, both formulations indicated presence of PPMs and SPMs of all categories and due to high phenolic and flavonoid content in IBT it showed high TPC and TFC content and better antioxidant properties then IBHEC. Both IBT and IBHEC showed good adaptogenic properties and also produced significant anti-inflammatory effects (decrease in edema) when compared with Indomethacin (standard drug). |
| Keywords: | Antioxidant, anti-inflammatory, Immunomodulators, Immunosuppressants, Immunoadjuvants, total phenolic content, total flavonoid content. |
| Cite Article: | "Comparative Pharmacological Assessment of Polyherbal Formulation Immunoboost Tablet and Immunoboost Herbal Extract Capsule", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 9, page no.806 - 828, September-2023, Available :http://www.ijsdr.org/papers/IJSDR2309121.pdf |
| Downloads: | 000251459 |
| Publication Details: | Published Paper ID: IJSDR2309121 Registration ID:208663 Published In: Volume 8 Issue 9, September-2023 DOI (Digital Object Identifier): Page No: 806 - 828 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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