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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Issue: September 2023

Volume 8 | Issue 9

Impact factor: 8.15

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Paper Title: Pharmacological Investigations of Ethanolic Roots Extract of Asparagus racemosus Willd
Authors Name: Pratibha Singh , Amrita Singh , Muskan Saxena , Bhanu P. S. Sagar
Unique Id: IJSDR2309120
Published In: Volume 8 Issue 9, September-2023
Abstract: Identity and purity of shatavari roots were established pharmacognostically and herbarium specimen IEC/Pharm/Herb/2022/2224 was deposited in Herbarium Bank. Shatavari roots confirmed phenolic compounds, alkaloids, sterols, flavanoids, steroidal glycosides isoflavones, and tannins. In physicochemical analysis of roots of Asparagus racemosus, roots were free from contamination (low ash values), AIAV 1.6 % (Low acid-insoluble ash values) indicated drug was free from siliceous matters / sand, WSAV 4.42 % (Water soluble ash value) indicated presence of water soluble salts and ASEV (7.94 %), WSEV (8.62%) (solvent extractive values) indicated presence of phyto-constituents and 2.68% (LOD). Asparagus racemosus Willd. EERAR extract induced powerful Rat RBC membrane stabilizing property (45.24% to 86.56% membrane stabilization impact of EERAR). Asparagus racemosus Willd. (shatavari) EERAR (A/B) produced impactful anti-inflammatory activity. The indomethacin induced excellent anti-inflammatory (edema reduced significantly). Asparagus racemosus Willd. EERAR roots extract contains phenolics, sterols and flavonoids possess significant inflammatory effects. Indomethacin and EERAR-B anti-inflammatory effects were very good in comparison of drug vehicle control group (significant at P<0.05 over control). Further, in Cotton pellet-induced granuloma method, Indomethacin (10 mg/kg) inhibition 53.20% ; EERAR-B: (400 mg/kg) inhibition 32.82%; values were significant at p < 0.05).
Keywords: Anti-inflammatory, carageenan, flavonoids, herbal medicines, indomethacin, natural products. paw edema, physicochemical, shatavari, solvent extractive values
Cite Article: "Pharmacological Investigations of Ethanolic Roots Extract of Asparagus racemosus Willd", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 9, page no.785 - 805, September-2023, Available :http://www.ijsdr.org/papers/IJSDR2309120.pdf
Downloads: 000251453
Publication Details: Published Paper ID: IJSDR2309120
Registration ID:208662
Published In: Volume 8 Issue 9, September-2023
DOI (Digital Object Identifier):
Page No: 785 - 805
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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