IN VITRO EVALUATION OF ANTI INFLAMMATORY AND ANTI HISTAMINE ACTIVITY OF SIDDHA FORMULATION KARAPPAN ENNAI.

RAHUL M , SIMAL S , GNANASEKAR D

Inflammation,Skin disease,Karappan ennai,Anti inflammatory,Antihistamine

Skin is the first line of defence in the body. Inflammation has become a risk factor for various disease. Nowdays the uses of traditional herbs in the treatment of inflammation has effects on different stages of inflammation including production of cytokines, dysregulation of cellular signalling and reduces the risk of barrier mechanism.It is only in recent times we have been able to employ scientific methods to prove the efficacy of the traditional herbs which tries give us better understanding of the mechanism of action for the herbs used in various dermatological condition.Bio active compounds from the medicine karappan ennai work in action by reducing the signs of inflammation including edema , regulating cellular activities , targeting major signalling pathways related to inflammation.Itching is one the commonest symptom associated with inflammatory skin disease, a more or less voluntary ,often subconscious motor activity to counteract the itch by slightly painful stimuli.The main indications for antihistamines in skin are suppression of pruritis in atopic dermatitis which are associated with increased mast cell numbers and tissue histamine levels.This review tries to be an account of anti-inflammatory activity and anti-histamine activity in karappan ennai with ingredients karunochi(Vitexnegundo),Vellaipoondu (alliumsativum), vasambu (acorus calamus) karunseeragam (nigella sativa), kadukkai (terminalia chebula),sitramanaku ennai (ricinus communis) Which acts against the signs of inflammation and possess anti histamine effects.

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"IN VITRO EVALUATION OF ANTI INFLAMMATORY AND ANTI HISTAMINE ACTIVITY OF SIDDHA FORMULATION KARAPPAN ENNAI.", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 9, page no.746 - 749, September-2023, Available :https://ijsdr.org/papers/IJSDR2309114.pdf

Volume 8 Issue 9, September-2023

Pages : 746 - 749

Paper Reg. ID: IJSDR_208495

Published Paper Id: IJSDR2309114

Downloads: 000347400

Research Area: Medical Science

Country: CHENNAI, TAMILNADU, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2309114

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2309114

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

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Publisher: IJSDR(IJ Publication) Janvi Wave

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