International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15

Issue: September 2023

Volume 8 | Issue 9

Impact factor: 8.15

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Paper Title: Cisplatin induced Nephrotoxicity and their herbal remedy:A review
Authors Name: Dr.Nihal Naimuddin Shaikh
Unique Id: IJSDR2309006
Published In: Volume 8 Issue 9, September-2023
Abstract: Cisplatin is a major antineoplastic drug for the treatment of tumors, but it has dose-dependent renal toxicity. However, its primary dose-limiting side effect is kidney injury, which is a major clinical concern. To help understand mechanisms involved in the development of kidney injury, cisplatin rodent model has been developed. At present, there are no effective drugs or methods for cisplatin-induced kidney injury. Recent in vitro and in vivo studies show that numerous herbal remedies such as flavonoids, saponins, alkaloids, polysaccharide, phenylpropanoids, etc. have specific antioxidant, anti-inflammatory, and anti-apoptotic properties that regulate the pathways associated with cisplatin-induced kidney damage. In this review we describe the molecular mechanisms of cisplatin induced nephrotoxicity and summarize recent findings in the field of herbal remedies that detrmine these mechanisms to protect against cisplatin-induced kidney damage and provide potential strategies for their treatment.
Cite Article: "Cisplatin induced Nephrotoxicity and their herbal remedy:A review ", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 9, page no.33 - 37, September-2023, Available :http://www.ijsdr.org/papers/IJSDR2309006.pdf
Downloads: 000251442
Publication Details: Published Paper ID: IJSDR2309006
Registration ID:208143
Published In: Volume 8 Issue 9, September-2023
DOI (Digital Object Identifier):
Page No: 33 - 37
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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