Paper Title

Cisplatin induced Nephrotoxicity and their herbal remedy:A review

Authors

Dr.Nihal Naimuddin Shaikh

Keywords

Abstract

Cisplatin is a major antineoplastic drug for the treatment of tumors, but it has dose-dependent renal toxicity. However, its primary dose-limiting side effect is kidney injury, which is a major clinical concern. To help understand mechanisms involved in the development of kidney injury, cisplatin rodent model has been developed. At present, there are no effective drugs or methods for cisplatin-induced kidney injury. Recent in vitro and in vivo studies show that numerous herbal remedies such as flavonoids, saponins, alkaloids, polysaccharide, phenylpropanoids, etc. have specific antioxidant, anti-inflammatory, and anti-apoptotic properties that regulate the pathways associated with cisplatin-induced kidney damage. In this review we describe the molecular mechanisms of cisplatin induced nephrotoxicity and summarize recent findings in the field of herbal remedies that detrmine these mechanisms to protect against cisplatin-induced kidney damage and provide potential strategies for their treatment.

How To Cite

"Cisplatin induced Nephrotoxicity and their herbal remedy:A review ", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 9, page no.33 - 37, September-2023, Available :https://ijsdr.org/papers/IJSDR2309006.pdf

Issue

Volume 8 Issue 9, September-2023

Pages : 33 - 37

Other Publication Details

Paper Reg. ID: IJSDR_208143

Published Paper Id: IJSDR2309006

Downloads: 000347085

Research Area: Medical Science

Country: Pandharpur , Maharashtra , India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2309006

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2309006

About Publisher

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

Article Preview

academia
publon
sematicscholar
googlescholar
scholar9
maceadmic
Microsoft_Academic_Search_Logo
elsevier
researchgate
ssrn
mendeley
Zenodo
orcid
sitecreex