INVITRO ANTIFUNGAL STUDY ON EXTRACTS OF A POLYHERBAL FORMULATION, “DADRUHARA LEPA” WITH SPECIAL REFERENCE TO RINGWORM (TINEA)

Dr. Sharad Gautam , Dr. D. S. Agrawal , Dr. Prafful Songara

Ringworm, antifungal, T.rubrum, T.verrucosum. Ayurvedic Lepa, Dadruhar Lepa

Ringworm (Tinea) is a most common dermatological problem affecting large number of population. T.rubrum and T.verrucosum is one of the most prevailing causative species. Tinea infection affects person’s social & personal hygienic health. It is the most recurrent disease. There are many medicines indicated orally for this but the importance of external application of medicated paste (lepa) is specifically indicated. One of the most accepted clinical ancient text Ashtang Hridaya by Acharya Vagbhatt mentioned polyherbal combination Dadruhara lepa (DHL) for the management of Dadru (Ringworm). The effect of DHL on ringworm is the synergistic action of soluble alkaloids & other active components of mixture, therefore invitro study of aqueous & hydroalcoholic extracts of DHL against T.rubrum & T.verrucosum was carried out to evaluate the antifungal activity of the DHL. Both the extracts showed significant antifungal activity against the selected dermatophytes. Study was carried through Agar well diffusion method. The maximum inhibition zone against T.rubrum & T.verrucosum for the hydro-alcoholic extract at 40mg/ml was 36 mm & 40 mm respectively, whereas aqueous extract showed maximum inhibition zone of 24mm and 26mm at same concentration against both dermatophytes.

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"INVITRO ANTIFUNGAL STUDY ON EXTRACTS OF A POLYHERBAL FORMULATION, “DADRUHARA LEPA” WITH SPECIAL REFERENCE TO RINGWORM (TINEA)", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 8, page no.1042 - 1047, August-2023, Available :https://ijsdr.org/papers/IJSDR2308154.pdf

Volume 8 Issue 8, August-2023

Pages : 1042 - 1047

Paper Reg. ID: IJSDR_208349

Published Paper Id: IJSDR2308154

Downloads: 000347193

Research Area: Other

Country: BHOPAL, MADHYA PRADESH, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2308154

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2308154

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

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