K.Malleswari
, D.Rama Brahma Reddy , Allamudi Pallavi , Ampirayani Harika , Angadala Pujitha
drug stability, protein fibrillation, drug delivery system
The increasing use of recombinantly expressed therapeutic proteins in the pharmaceutical industry has highlighted issues such as their stability during long-term storage and means of efficacious delivery that avoid adverse immunogenic side effects. Controlled chemical modifications, such as substitutions, acylation and PEGylation, have fulfilled some but not all of their promises, while hydrogels and lipid-based formulations could well be developed into generic delivery systems. Strategies to curb the aggregation and misfolding of proteins during storage are likely to benefit from the recent surge of interest in protein fibrillation. This might in turn lead to generally accepted guidelines and tests to avoid unforeseen adverse effects in drug delivery. Drugs are substances that change a person's mental or physical state. They can affect the way your brain works, how you feel and behave, your understanding and your senses. This makes them unpredictable and dangerous, especially for young people. The effects of drugs are different for each person and drug. Drug education helps children and young people understand that all drugs, legal and illegal, have the potential to cause harm, and that the drug experience is because of many factors including the person, the drug and the environment.
"DRUG STABILITY", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 8, page no.941 - 948, August-2023, Available :https://ijsdr.org/papers/IJSDR2308138.pdf
Volume 8
Issue 8,
August-2023
Pages : 941 - 948
Paper Reg. ID: IJSDR_208253
Published Paper Id: IJSDR2308138
Downloads: 000347224
Research Area: Engineering
Country: -, -, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
