Recent advances in cyclodextrin based transdermal drug delivery

Neha Chauhan , Sahil Singh , Manpreet kaur walia

Cyclodextrin, Transdermal Drug Delivery System, Hydrogel, Microneedles, Patch

This review addresses case studies incorporating hydro gel, gel patch, micro needles, and liposome micro emulsion to provide a thorough overview of current developments in Cyclodextrins-based transdermal drug delivery. Cyclodextrins have emerged as adaptable excipients with the potential to improve medication transport over the skin as transdermal drug delivery has grown in popularity as a non-invasive and patient-friendly route of administration. The case studies examine how Cyclodextrins are included into each delivery system and look at how they affect the drug's solubility, stability, and permeability. In particular, the addition of cyclodextrin into hydro gel formulations exhibits improved drug penetration and sustained release characteristics, whereas gel patches accomplish controlled drug release and extended skin residence. Drug distribution that is precise and targeted is made possible by integration with micro needles thanks to the development of inclusion complexes. Additionally, better drug encapsulation and release properties are shown by cyclodextrin-stabilized liposome micro emulsions. The paper also discusses production issues and safety concerns, offering insightful information on how cyclodextrin-based transdermal drug delivery systems may revolutionize medication administration for better therapeutic results.

Published Paper   E-Certificate

"Recent advances in cyclodextrin based transdermal drug delivery", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 8, page no.490 - 498, August-2023, Available :https://ijsdr.org/papers/IJSDR2308071.pdf

Volume 8 Issue 8, August-2023

Pages : 490 - 498

Paper Reg. ID: IJSDR_208175

Published Paper Id: IJSDR2308071

Downloads: 000347216

Research Area: Pharmacy

Country: Hamirpur, Himachal Pradesh, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2308071

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2308071

DOI: http://doi.one/10.1729/Journal.35858

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition