DEVELOPMENT OF INVASOMAL GEL FOR THE TREATMENT OF ACNE VULGARIS

Mr.Rohit Dharmadas Zoad , Prof.Bhutada Chetan , Mr. Tushar P. Akhare , Dr. Lahu D. Hingane , Miss Shruti Ravindra Thakre

Acne vulgaris, CAME, Invasomal gel

The most common skin issue from a variety of causes, acne vulgaris—commonly known as acne—has a higher frequency in teens. As a result of androgen-induced increased sebum production, altered keratinization, inflammation, and Propionibacterium acnes bacterial colonization of hair follicles on the face, neck, chest, and back, acne is a chronic inflammatory illness of the pilosebaceous unit. Seborrhoea (excess grease), non-inflammatory lesions (open and closed comedones), inflammatory lesions (papules and pustules), and varying degrees of scarring are some of the clinical characteristics of acne. One prospective research of 133 kids aged 5.5 to 12 years, followed for an average of 2.5 years, discovered that at first, just a small number of glands in the face were producing sebum, but as time went on, more and more glands began to do so. Unsaturated phosphatidyl choline, a minor amount of ethanol, and a small quantity of a blend of terpenes (cinnamic acid, citral, and d-limonene) made up the invadesomes. In an ethanolic phospholipid solution, the drug is combined with terpenes, or terpene combinations, for dissolution. To get a clear solution, the mixture is vortexed for 5 min, followed by 5 min of sonication. Phosphate buffer saline (PBS) (pH: 7.4) is continuously injected into the solution using a syringe.

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"DEVELOPMENT OF INVASOMAL GEL FOR THE TREATMENT OF ACNE VULGARIS", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 8, page no.448 - 460, August-2023, Available :https://ijsdr.org/papers/IJSDR2308065.pdf

Volume 8 Issue 8, August-2023

Pages : 448 - 460

Paper Reg. ID: IJSDR_208150

Published Paper Id: IJSDR2308065

Downloads: 000347279

Research Area: Pharmacy

Country: BEED, MAHARASHTRA, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2308065

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2308065

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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