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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | COMPARITIVE STUIDY BETWEEN NATAMYCIN AND NATAMYCIN WITH VORICONAZOLE IN TREATMENT OF FUNGAL CORNEAL ULCER |
| Authors Name: | Dr.Mrudula Raj. Vanga , G. Jaya Sri Durga , G. Jyothirmayee |
| Unique Id: | IJSDR2307022 |
| Published In: | Volume 8 Issue 7, July-2023 |
| Abstract: | One of the sense organs Eye is connected to the mind and to interpret what we are seeing .View of eye depends upon the switch of mild. This light passes through the cornea to the lens. The cornea and the lens helps to awareness the light rays onto the lower back of the eye (retina). The cells inside the retina absorbs and light is converted to electro chemical impulses which are transferred alongside the optic nerve after which to the brain. The cornea consists of proteins and cells and not include blood vessels. The cornea is constituted of 5 layers: Epithelium, Bowman’s layer, Stroma, Descemet’s membrane, Endothelium..A corneal ulcer is an open sore located on cornea. Fungal corneal ulcer refers to an infective method of the cornea due to any of the a couple of pathological fungi capable of invading the ocular floor. In this study duration we've evaluated 96 sufferers on fungal corneal ulcer . The present examine shows efficacy between Natamycin and Natamycin with Voriconazole in fungal corneal ulcer sufferers. 96 patients with corneal ulcer and fungal elements visible on smear had been assessed eligibility at some point of the period from November 2021 to April 2022 and 16 patients were excluded. Among all of the patients, male are 50 and woman are 30 . Quantity of male patients given with single therapy are 28 and aggregate therapy are 22 range of female patients given with single drug therapy are 12 and combination therapy are 18.Overall wide variety of patient passed through surgical operation are 30. Among them single therapy taking people are 22 and combination therapy taking people are 8 . We've determined that people who are working in agriculture fields are more distinguished to fungal corneal ulcer and who take topical steroid eye drops has proven to growth size and depth of corneal ulcer. Diabetes is likewise one of the threat element in those patients because it delays the healing of ulcer. By way of looking at all of the outcomes 30% of the human beings in aggregate remedy were given healed in third visit whereas only 12.5% of people with single remedy. Only 5% of people took up to four weeks to remedy in combination therapy, while 17.5e% humans in single therapy..When compared with those who received Natamycin and Natamycin with Voriconazole – treated patients had an approximately first line improvement. |
| Keywords: | Epithelium, electro chemical impulse , Fungal corneal ulcer , steroid eye drops, Diabetes. |
| Cite Article: | "COMPARITIVE STUIDY BETWEEN NATAMYCIN AND NATAMYCIN WITH VORICONAZOLE IN TREATMENT OF FUNGAL CORNEAL ULCER", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 7, page no.155 - 167, July-2023, Available :http://www.ijsdr.org/papers/IJSDR2307022.pdf |
| Downloads: | 000338536 |
| Publication Details: | Published Paper ID: IJSDR2307022 Registration ID:207582 Published In: Volume 8 Issue 7, July-2023 DOI (Digital Object Identifier): Page No: 155 - 167 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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