ASSESSMENT OF SERUM ELECTROLYTE CHANGES (Na+, K+, Ca++, Mg++) IN PATIENTS WHO HAVE BEEN POISONED WITH ALUMINUM PHOSPHIDE
Ramesh Laxman Gothwal
, N.L Disania , Sandeep , Minali Ramesh , Priyank Gupta
AlP, POISOING, SERUM ELECTROLYTES, CELPHOS
BACKGROUND: The most lethal phosphide, aluminium phosphide also known as AlP, is used to transport and store grains safely, particularly in Asian, Middle Eastern, and African nations. In India, it is marketed as tablets of quickphos, celphos, alphos, and phostoxin and also in the form of powder in sachets. When Aluminium phosphide (AlP) tablets are exposed to humidity, phosphine gas (PH3), a very poisonous gas, is produced. Phosphine (PH3), can cause lipid peroxidation and limit cellular oxygen use. During suicide attempts, Aluminium phosphide (AlP) poisoning has occurred usually, more common in adults than in teenagers. MATERIALS AND METHODS: The present analytical study comprised of 59 acute aluminium phosphide (AlP) poisoning patients as per history given by patients/relatives, admitted in a medical emergency at S.M.S Medical College, Jaipur. The details of the history and physical examination were recorded, and relevant lab investigations were done. The serum electrolytes were evaluated at the time of admission in all the AlP poisoning patients. There were 50 healthy control subjects evaluated for serum electrolytes measurement. RESULTS: The study of 59 acute AlP poisoning patients showed 57.8% cases presented with hyponatremia in comparison to 42.2% cases with hypernatremia; 92.8% cases were hypokalemic in comparison to 7.2% hypokalemic cases; 85.2% cases were hypocalcaemia in comparison to 14.8% cases with hypercalcaemia; and 70.6% cases presented with hypomagnesemia in comparison to 29.4% cases with hypermagnesemia. There is no statistical difference in serum Na+ and K+ values between recovery and fatality consequent to AlP poisoning patients of the present study. However, serum Mg++ and calcium levels were higher in expired patients in comparison to recovered patients. CONCLUSION: In the study, various significant electrolyte changes were found in the AlP poisoning patients. But as evident from the study, there is no correlation between serum electrolyte levels and mortality or survival of AlP poisoning patients.
"ASSESSMENT OF SERUM ELECTROLYTE CHANGES (Na+, K+, Ca++, Mg++) IN PATIENTS WHO HAVE BEEN POISONED WITH ALUMINUM PHOSPHIDE", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 5, page no.2221 - 2225, May-2023, Available :https://ijsdr.org/papers/IJSDR2305352.pdf
Volume 8
Issue 5,
May-2023
Pages : 2221 - 2225
Paper Reg. ID: IJSDR_206890
Published Paper Id: IJSDR2305352
Downloads: 000347292
Research Area: Medical Science
Country: Jaipur, RAJASTHAN, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave