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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Issue: May 2023

Volume 8 | Issue 5

Impact factor: 8.15

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Paper Title: Investigating the effectiveness of Benzamide Derivatives as Anti-TB Agents: a Comparative Analysis with Existing Drugs
Authors Name: Abhishikta Chakladar , Chinmay Pandey , Yash Bhandari
Unique Id: IJSDR2305031
Published In: Volume 8 Issue 5, May-2023
Abstract: This research investigates the potential of benzamide derivatives as anti-TB agents. A total of 72 molecules were designed by substituting some Quinazoline derivatives, which have previously shown good anti-tubercular activities. These molecules were then subjected to pharmacokinetic studies using Swiss ADME software. To further evaluate their effectiveness, the designed molecules were docked using Molegro Virtual Docker to study their amino-acid interactions with target proteins. The results showed that some of the designed molecules had promising amino-acid interactions and could potentially be effective anti-TB agents. This study provides valuable insights into the development of new drugs to combat TB.
Keywords: Benzamide derivatives, anti-TB agents, Quinazoline derivatives, pharmacokinetic studies using Swiss ADME software, Molegro Virtual Docker docking, amino-acid interactions with target proteins, 4U0K,4U0J, tuberculosis.
Cite Article: "Investigating the effectiveness of Benzamide Derivatives as Anti-TB Agents: a Comparative Analysis with Existing Drugs", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 5, page no.206 - 223, May-2023, Available :http://www.ijsdr.org/papers/IJSDR2305031.pdf
Downloads: 000222060
Publication Details: Published Paper ID: IJSDR2305031
Registration ID:205994
Published In: Volume 8 Issue 5, May-2023
DOI (Digital Object Identifier):
Page No: 206 - 223
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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