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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH
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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Issue: April 2024

Volume 9 | Issue 4

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Paper Title:	Self Microemulsifying Drug Delivery System: A Review
Authors Name:	Sonal Sunil Salunke , Akshay Sanjay Chikate , K.B.Burade
Unique Id:	IJSDR2304379
Published In:	Volume 8 Issue 4, April-2023
Abstract:	Self-micro emulsifying drug delivery systems are designed for drugs having pre-systemic first-pass effects, high molecular weights, gastric irritability, enzymatic degradation, slow rates of dissolution, and lower bioavailability. Due to the drug's solubilization in lipidic excipients, which skips the dissolving stage, the generated emulsion delivers faster absorption, faster dissolution rates, and excellent bioavailability, making this method ideal for practically all drugs. SMEDDS, or self-micro emulsifying drug delivery systems, are isotropic blends of natural or synthetic oils, solid or liquid surfactants, or alternatively one or more hydrophilic solvents and co-solvents/surfactants. The review covered the mechanism of self-emulsification in detail as well as the construction of a pseudo ternary phase diagram, the formulation of SMEDDS, its solidification techniques, its characterization, the advantages of SMEDDS over emulsion, and the limitations as well as applications of SMEDDS. This review article wil
Keywords:	Self-Microemulsifying drug delivery system, Surfactant, Co-surfactant, Pseudo-ternary phase diagram.
Cite Article:	"Self Microemulsifying Drug Delivery System: A Review", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.2430 - 2442, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304379.pdf
Downloads:	000337067
Publication Details:	Published Paper ID: IJSDR2304379 Registration ID:205796 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): Page No: 2430 - 2442 Publisher: IJSDR \| www.ijsdr.org ISSN Number: 2455-2631

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