Role of Magnetic Resonance Imaging in Early Progressive Dementia in diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)

Mahender Reddy Yasa , Manasa Ravipati , Sudhakar Katojju

CADASIL, MRI, computed tomography, white matter hyperintensities, cerebral microbleeds.

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is an autosomal dominant vascular disorder. Diagnosis and follow-up in patients with CADASIL are based mainly on magnetic resonance imaging (MRI). MRI shows white matter hyperintensities (WMHs). WMHs lesions tend to be symmetrical and bilateral, distributed in the periventricular and deep white matter. The anterior temporal lobe and external capsules are predilection sites for WMHs, with higher specificity and sensitivity of anterior temporal lobe involvement compared to an external capsule involvement. Lacunar infarcts are presented by an imaging signal that has intensity of cerebrospinal fluid in all MRI sequences. They are localized within the semioval center, thalamus, basal ganglia and pons. CMBs are depicted as focal areas of signal loss on T2 images which increases in size on the T2*-weighted gradient echo planar images (“blooming effect”).

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"Role of Magnetic Resonance Imaging in Early Progressive Dementia in diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 3, page no.1040 - 1042, March-2023, Available :https://ijsdr.org/papers/IJSDR2303172.pdf

Volume 8 Issue 3, March-2023

Pages : 1040 - 1042

Paper Reg. ID: IJSDR_204724

Published Paper Id: IJSDR2303172

Downloads: 000347199

Research Area: Medical Science

Country: Chennai, TamilNadu, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2303172

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2303172

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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