METHANOLIC ROOT EXTRACT OF CITRULLUS COLOCYNTHIS AMELIORATE PARKINSON`S DISEASE IN EXPERIMENTAL ANIMALS

Pushpendra Ahirwar , Yashwant Singh , Abhijit Sahana , Pooja Shrivastava

Citrullus Colocynthis Ameliorate, Natural Product, α-Synuclein, Methanolic Root Extract

Parkinson’s disease (PD) is made, and a significant loss of dopaminergic neurons has already occurred. Identifying patients in the period between the presumed onset of dopaminergic cell loss and the appearance of clinical parkinsonism may be of major importance in the development of effective neuroprotective treatment strategies. In an effort to develop a feasible strategy to detect preclinical PD, a combination of olfactory processing tasks, including odor detection, odor identification, and odor discrimination was used to select groups of hyposmic and normosmic individuals from a total of 250 relatives (parents, siblings, or children) of subjects with PD.α-Synuclein (α-syn) aggregation is central to neuropathological changes in Parkinson’s disease. The aggregates spread within the central nervous system according to a very predictable pattern. A prion-like transmission of α-syn aggregates has been recently proposed to explain this propagation pattern.

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"METHANOLIC ROOT EXTRACT OF CITRULLUS COLOCYNTHIS AMELIORATE PARKINSON`S DISEASE IN EXPERIMENTAL ANIMALS", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 3, page no.883 - 891, March-2023, Available :https://ijsdr.org/papers/IJSDR2303142.pdf

Volume 8 Issue 3, March-2023

Pages : 883 - 891

Paper Reg. ID: IJSDR_204658

Published Paper Id: IJSDR2303142

Downloads: 000347510

Research Area: Medical Science

Country: Sagar, Madhya Pradesh, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2303142

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2303142

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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