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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.15 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Panoramic review on mammary carcinomic chemopreventive animal models |
| Authors Name: | K.Monica , DR.G.Ariharasivakumar , G.M.Mathiazhagan , E.Santhosh kumar , R.Vinoth kumar |
| Unique Id: | IJSDR2303077 |
| Published In: | Volume 8 Issue 3, March-2023 |
| Abstract: | Consequently, animal models are utilised to evaluate the effectiveness of chemopreventive and chemotherapeutic drugs. This is due to the fact that the microenvironment of primary cells that have been cultured and separated from an animal organ or system differs significantly from in vitro systems. To better understand how various cell types and drug or xenobiotic metabolisms interact, animal models are essential. Animal models can be produced chemically or transgenetically to study particular cancer types. There are several tumor-specific animal models available for research on chemopreventive effects. In several chemically produced or transgenic animal models, the effectiveness of chemotherapeutic medications used to treat malignancies such as prostate, skin, liver, and colon, among others, is being studied. In women, breast cancer is the most prevalent type of malignancy. Animal experimentation is a major part of basic and translational breast cancer research. Such breast cancer models should, in theory, be similar to human breast cancer in terms of tumour origin, biological behaviour, pathology, and therapeutic response. This study describes recent developments in several breast cancer experimental animal models and examines their traits, benefits, and future uses. Finally, we suggest future lines of investigation for animal models of breast cancer. |
| Keywords: | Drug development; Metastasis; Animal models; Breast cancer. |
| Cite Article: | "Panoramic review on mammary carcinomic chemopreventive animal models ", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 3, page no.504 - 509, March-2023, Available :http://www.ijsdr.org/papers/IJSDR2303077.pdf |
| Downloads: | 00023 |
| Publication Details: | Published Paper ID: IJSDR2303077 Registration ID:204406 Published In: Volume 8 Issue 3, March-2023 DOI (Digital Object Identifier): Page No: 504 - 509 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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