Panoramic review on mammary carcinomic chemopreventive animal models

K.Monica , DR.G.Ariharasivakumar , G.M.Mathiazhagan , E.Santhosh kumar , R.Vinoth kumar

Drug development; Metastasis; Animal models; Breast cancer.

Consequently, animal models are utilised to evaluate the effectiveness of chemopreventive and chemotherapeutic drugs. This is due to the fact that the microenvironment of primary cells that have been cultured and separated from an animal organ or system differs significantly from in vitro systems. To better understand how various cell types and drug or xenobiotic metabolisms interact, animal models are essential. Animal models can be produced chemically or transgenetically to study particular cancer types. There are several tumor-specific animal models available for research on chemopreventive effects. In several chemically produced or transgenic animal models, the effectiveness of chemotherapeutic medications used to treat malignancies such as prostate, skin, liver, and colon, among others, is being studied. In women, breast cancer is the most prevalent type of malignancy. Animal experimentation is a major part of basic and translational breast cancer research. Such breast cancer models should, in theory, be similar to human breast cancer in terms of tumour origin, biological behaviour, pathology, and therapeutic response. This study describes recent developments in several breast cancer experimental animal models and examines their traits, benefits, and future uses. Finally, we suggest future lines of investigation for animal models of breast cancer.

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"Panoramic review on mammary carcinomic chemopreventive animal models ", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 3, page no.504 - 509, March-2023, Available :https://ijsdr.org/papers/IJSDR2303077.pdf

Volume 8 Issue 3, March-2023

Pages : 504 - 509

Paper Reg. ID: IJSDR_204406

Published Paper Id: IJSDR2303077

Downloads: 000347250

Research Area: Pharmacy

Country: COIMBATORE, Tamil Nadu, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2303077

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2303077

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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