International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15

Issue: November 2023

Volume 8 | Issue 11

Impact factor: 8.15

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Paper Title: How cancer drugs are discovered and developed
Authors Name: G.M.Mathiazhagan , DR.G.Ariharasivakumar , K.Monica , E.Santhosh kumar , R.Vinoth kumar
Unique Id: IJSDR2303060
Published In: Volume 8 Issue 3, March-2023
Abstract: Cancer may be a complex malady and its genesis and progression are extraordinarily complex.The largest downside within the malignant neoplasm drug development is deed of multi drug resistance and relapse. Classical chemo therapeutics directly target the polymer of the cell, whereas the modern anticancer medication involve molecular-targeted medical care reminiscent of targeting the proteins possessing abnormal expression within the cancer cells.Standard ways for the complete demolition of the cancer cells tested ineffective.Targeted therapy was successful in bound malignancies however, the effectiveness has usually been restricted by drug resistance and side effects on traditional tissues and cells.Since previous few years, several promising drug targets are known for the effective treatment of cancer. This review article describes a number of these promising malignant neoplasm targets that embrace kinases, tubulin, cancer stem cells, being antibodies and microtuble targeting agents. In addition, promising drug candidates underneath varied phases of clinical trials also are described. Multi-acting medication that simultaneously target completely different neoplastic cell signal pathways might facilitate the method of effective anti-cancer drug development
Keywords: Anticancer, Various target statergies, Tubulin, Kinases, Cancer stem cell, Monoclonal antibodies.
Cite Article: "How cancer drugs are discovered and developed", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 3, page no.388 - 395, March-2023, Available :http://www.ijsdr.org/papers/IJSDR2303060.pdf
Downloads: 000314594
Publication Details: Published Paper ID: IJSDR2303060
Registration ID:204404
Published In: Volume 8 Issue 3, March-2023
DOI (Digital Object Identifier):
Page No: 388 - 395
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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