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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | To developed and optimized formulation of Lansoprazole Enteric Coated Pellets drug delivery system by using polymer |
| Authors Name: | Akshata Sanjy Patil |
| Unique Id: | IJSDR2302024 |
| Published In: | Volume 8 Issue 2, February-2023 |
| Abstract: | Lansoprazole is a proton siphon inhibitor utilized in treating gastric ulcers and gastro esophageal reflux Disease (GERD) and furthermore keeping up with of all grades of erosive esophagitis (EE). Proton pump inhibitors are corrosive labile medications. These medications will debase in acidic climate of stomach and will prompt restorative inefficacy. lansoprazole is profoundly corrosive labile and presents numerous plan difficulties and to safeguard it from acidic climate of the stomach. It is important to sidestep the acidic pH of the stomach, which can be accomplished by planning postponed discharge measurement structures (single unit or numerous units) by utilizing different intestinal polymers. Lansoprazole and excipients of different like HPC-L and eudragit L30 D55 were utilized as intestinal polymers. The intestinal covered pellets were ready by suspension layering strategy in fluidized bed processor (FBP). Nine Definitions of lansoprazole intestinal covered pellets were arranged differing the syntheses of medication stacking, boundary covering and intestinal covering. Corrosive protections concentrate on shows that the advanced definition F9 is more steady in the acidic media for example 96.73% of medication was delivered in an hour. The point of the current review was to create a chemically same, stable, cost of powerful and quality superior definition of lansoprazole deferred discharge pellets. The pre-arranged pellets were read up for their physico-compound properties, examine and in vitro release studies. |
| Keywords: | Lansoprazole, Enteric Coated Pellets, eudragit, Accelerated stability |
| Cite Article: | "To developed and optimized formulation of Lansoprazole Enteric Coated Pellets drug delivery system by using polymer", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 2, page no.126 - 134, February-2023, Available :http://www.ijsdr.org/papers/IJSDR2302024.pdf |
| Downloads: | 000337214 |
| Publication Details: | Published Paper ID: IJSDR2302024 Registration ID:203852 Published In: Volume 8 Issue 2, February-2023 DOI (Digital Object Identifier): Page No: 126 - 134 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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