Pattern of Adverse Drug Reactions with DOTS regime in Pulmonary Tuberculosis at tertiary care teaching hospital, Kanpur
Kriti Jalota
, Nilam Nigam , Shweta Tripathi , Prachi Jalota , Ruchika Agarwal
Aim: our study aimed at recognising the patterns of ADR prevalent in our tertiary care teaching hospital and research, Kanpur with the implementation of DOTS regime in new Pulmonary TB. Material & Methods: It was a prospective observational study conducted in the department of Pharmacology in association of Department of Medicine in tertiary care teaching hospital and research centre, Rama Medical College ,Kanpur UP. All the newly diagnosed Pulmonary tuberculosis adult patient enrolled for DOTS regime in intensive phase were followed up for ADRs. The causality and severity were determined by WHO and Hartwig’s algorithms respectively. Results: a total of hundred pulmonary tuberculosis patients were enrolled in our study following the inclusion criteria. A total of 125 ADRs were noted in these six months. Males(71%) had a higher ratio of ADRs than females(29%). Majority of the reactions were associated to the gastrointestinal tract system. Hepatitis(>3x) was serious ADR. Majority of the ADRs were of mild type (81.60 %) and were Probable in 88%. 79% of the patients did not require any modification in the standard regime due to ADRs. Conclusion: As healthcare workers it is ethically correct to be persuasive, convincing and supportive to the patients for continued treatment despite the mild Adverse Drug Reactions experienced in course. An influential education system of these patients’ under-treatment can improve the patient adherence and therapeutic outcome consequently reducing the morbidity and untimely mortality in our country.
"Pattern of Adverse Drug Reactions with DOTS regime in Pulmonary Tuberculosis at tertiary care teaching hospital, Kanpur", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 10, page no.158 - 160, October-2022, Available :https://ijsdr.org/papers/IJSDR2210029.pdf
Volume 7
Issue 10,
October-2022
Pages : 158 - 160
Paper Reg. ID: IJSDR_202032
Published Paper Id: IJSDR2210029
Downloads: 000347304
Research Area: Engineering
Country: -, -, -
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
