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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Comprehensive Review on Solid Lipid Nanoparticles |
| Authors Name: | Rahul B. Shinde , Prajakta M. Shinde , Dr. Avinash H. Hosmani |
| Unique Id: | IJSDR2206075 |
| Published In: | Volume 7 Issue 6, June-2022 |
| Abstract: | Solid lipid nanoparticles (SLN) have attracted attention during recent years. Solid lipid nanopaticles were developed in early 1990s as an alternative to other traditional colloidal carriers like liposomes, polymeric nanoparticles and emulsions as they have advantages like controlled drug release and targeted drug delivery with increased stability. The present review focuses on the utility of SLN in terms of their advantages & disadvantages, production methodology and characterization. The network of the SLNs improves drug stability and releasing the drug in a controlled way, which additionally offer a few advantages over ordinary details, including great physical stability, spherical morphology, uniform size, positive zeta potentials, typical high cell penetration efficiency, core–shell pattern and excipients of GRAS status make the SLNs delivery system all the more promising. Recently, increasing attention has been focused on these SLN as colloidal drug carriers for incorporating hydrophilic or lipophilic drugs. |
| Keywords: | Solid lipid nanoparticles, High pressure homogenizer, Solid lipid, Surfactants, Drug incorporation. |
| Cite Article: | "Comprehensive Review on Solid Lipid Nanoparticles", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 6, page no.467 - 475, June-2022, Available :http://www.ijsdr.org/papers/IJSDR2206075.pdf |
| Downloads: | 000346989 |
| Publication Details: | Published Paper ID: IJSDR2206075 Registration ID:200711 Published In: Volume 7 Issue 6, June-2022 DOI (Digital Object Identifier): Page No: 467 - 475 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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