Comprehensive Review on Solid Lipid Nanoparticles
Rahul B. Shinde
, Prajakta M. Shinde , Dr. Avinash H. Hosmani
Solid lipid nanoparticles, High pressure homogenizer, Solid lipid, Surfactants, Drug incorporation.
Solid lipid nanoparticles (SLN) have attracted attention during recent years. Solid lipid nanopaticles were developed in early 1990s as an alternative to other traditional colloidal carriers like liposomes, polymeric nanoparticles and emulsions as they have advantages like controlled drug release and targeted drug delivery with increased stability. The present review focuses on the utility of SLN in terms of their advantages & disadvantages, production methodology and characterization. The network of the SLNs improves drug stability and releasing the drug in a controlled way, which additionally offer a few advantages over ordinary details, including great physical stability, spherical morphology, uniform size, positive zeta potentials, typical high cell penetration efficiency, core–shell pattern and excipients of GRAS status make the SLNs delivery system all the more promising. Recently, increasing attention has been focused on these SLN as colloidal drug carriers for incorporating hydrophilic or lipophilic drugs.
"Comprehensive Review on Solid Lipid Nanoparticles", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 6, page no.467 - 475, June-2022, Available :https://ijsdr.org/papers/IJSDR2206075.pdf
Volume 7
Issue 6,
June-2022
Pages : 467 - 475
Paper Reg. ID: IJSDR_200711
Published Paper Id: IJSDR2206075
Downloads: 000347021
Research Area: Pharmacy
Country: Osmanabad, Maharashtra, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave