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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Simultaneous equation method for the estimaton of fluconazole and Ivermatin by UV spectrophotometry |
| Authors Name: | VISHAL UTTRESHWAR THODSARE , SAGER S. KALE |
| Unique Id: | IJSDR2206069 |
| Published In: | Volume 7 Issue 6, June-2022 |
| Abstract: | The simple, accurate, and precise UV spectrophotometric method has developed for simultaneous estimation of Fluconazole and Ivermectin in bulk tablet formulation. Two wavelength 273 nm and 253 nm were selected for estimation of Fluconazole and Ivermectin by simultaneous equation method respectively. UV spectrophotometric method was developed as per ICH guideline using O-phosphoric acid and water Mobile phase. Fluconazole and Ivermactin individually follows the Beer-Lamberts Law over concentration range 120-180 and 4.8-7.2μg/mL, regression of coefficient was found to be r2=0.9966 and r2=0.9954 respectively. The percentage recovery was found to be 98 to 101 % at three different levels. The proposed method was successfully applied for determination of Fluconazole and Ivermactin in tablet dosage form as per ICH guideline the result of the analysis were validated statistically and were found to be satisfactory. |
| Keywords: | Fluconazole , Ivermactin, Simultaneous equation, UV Spectrophotometer, Validation. |
| Cite Article: | "Simultaneous equation method for the estimaton of fluconazole and Ivermatin by UV spectrophotometry", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 6, page no.432 - 439, June-2022, Available :http://www.ijsdr.org/papers/IJSDR2206069.pdf |
| Downloads: | 000346986 |
| Publication Details: | Published Paper ID: IJSDR2206069 Registration ID:200688 Published In: Volume 7 Issue 6, June-2022 DOI (Digital Object Identifier): Page No: 432 - 439 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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