Simultaneous equation method for the estimaton of fluconazole and Ivermatin by UV spectrophotometry

VISHAL UTTRESHWAR THODSARE , SAGER S. KALE

Fluconazole , Ivermactin, Simultaneous equation, UV Spectrophotometer, Validation.

The simple, accurate, and precise UV spectrophotometric method has developed for simultaneous estimation of Fluconazole and Ivermectin in bulk tablet formulation. Two wavelength 273 nm and 253 nm were selected for estimation of Fluconazole and Ivermectin by simultaneous equation method respectively. UV spectrophotometric method was developed as per ICH guideline using O-phosphoric acid and water Mobile phase. Fluconazole and Ivermactin individually follows the Beer-Lamberts Law over concentration range 120-180 and 4.8-7.2μg/mL, regression of coefficient was found to be r2=0.9966 and r2=0.9954 respectively. The percentage recovery was found to be 98 to 101 % at three different levels. The proposed method was successfully applied for determination of Fluconazole and Ivermactin in tablet dosage form as per ICH guideline the result of the analysis were validated statistically and were found to be satisfactory.

Published Paper   E-Certificate

"Simultaneous equation method for the estimaton of fluconazole and Ivermatin by UV spectrophotometry", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 6, page no.432 - 439, June-2022, Available :https://ijsdr.org/papers/IJSDR2206069.pdf

Volume 7 Issue 6, June-2022

Pages : 432 - 439

Paper Reg. ID: IJSDR_200688

Published Paper Id: IJSDR2206069

Downloads: 000347069

Research Area: Pharmacy

Country: Solapur, Maharashtra, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2206069

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2206069

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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