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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Calcifying Epithelioma of Malharbe - Pilomatricoma - A Retrospective Study in a Tertiary Care Hospital |
| Authors Name: | DR. PARUL JAIN , DR.REETA DHAR , DR.RISHABH JAIN , DR.SHILPI SAHU |
| Unique Id: | IJSDR2112001 |
| Published In: | Volume 6 Issue 12, December-2021 |
| Abstract: | Background - Pilomatricoma, also known as pilomatrixoma, is a type of noncancerous (benign) skin tumor associated with hair follicles.It demonstrates a bimodal peak presentation during the first and sixth decades of life, 40% of cases occur in patients younger than 10 years of age and 60% of cases occur within the first two decades of life [1,2]. Pilomatricoma represents 0.12% of all skin tumors.[4]Its prevalence is poorly defined and its presentation varies and can simulate various other skin lesions also. Materials and Methods - This retrospective study was conducted to evaluate the clinical and histomorphology of pilomatricoma along with it’s incidence with respect to age, sex and site of lesion in a tertiary care hospital,Navi Mumbai . Following parameters were used to diagnose pilomatricoma 1.Shadow cells 2.Sebocytes 3.Matrical cells 4.Supramatrical cells 5.Isthmic differentiation 6.Infundibular differentiation 7.Calcification 8.Melanocytes 9.Basaloid epidermal proliferation 10.Trichohyaline granules 11.Outer sheath differentiation(clear cells) 12.Foreign body giant cells Results – A female preponderance with maximum cases in the 31 – 45 years age group was found in our study. The predominant site of lesion was head more specifically scalp followed by upper arm. The clinical diagnosis comprised of spectrum of lesions including dermoid cyst, sebaceous cyst ,unidentified lesion and inflammatory lymph node. Histological features of basaloid cells with eosinophillic ghost cells was found in almost all cases along with associated features of calcification and presence of giant cells. Conclusion – Pilomatricoma is not rare in occurrence but rarely diagnosed because of lack of confirmation of excised swelling. These are often mistaken for small round blue cell tumours in children, or for merkel cell carcinoma, basolioma and metastatic small cell carcinoma in adults, with possible aggressive therapeutic approach and hence, it is imperative that it should be kept in the differential diagnoses of all superficial skin tumors by dermatologists and surgeons. This study also helped in finding the prevalence of this disease in India, as there is paucity of the same in our country. Thus overall, this study helped in finding the various histomorphological features which are diagnostic of pilomatricoma . It also adds to the data of the disease in our country and will help in better clinical management as well as triage of patients. |
| Keywords: | Nodular Scalp swelling, Histopathology, Epithelioma of Malharbe |
| Cite Article: | "Calcifying Epithelioma of Malharbe - Pilomatricoma - A Retrospective Study in a Tertiary Care Hospital", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.6, Issue 12, page no.1 - 6, December-2021, Available :http://www.ijsdr.org/papers/IJSDR2112001.pdf |
| Downloads: | 000337071 |
| Publication Details: | Published Paper ID: IJSDR2112001 Registration ID:193733 Published In: Volume 6 Issue 12, December-2021 DOI (Digital Object Identifier): Page No: 1 - 6 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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