Calcifying Epithelioma of Malharbe - Pilomatricoma - A Retrospective Study in a Tertiary Care Hospital
DR. PARUL JAIN
, DR.REETA DHAR , DR.RISHABH JAIN , DR.SHILPI SAHU
Nodular Scalp swelling, Histopathology, Epithelioma of Malharbe
Background - Pilomatricoma, also known as pilomatrixoma, is a type of noncancerous (benign) skin tumor associated with hair follicles.It demonstrates a bimodal peak presentation during the first and sixth decades of life, 40% of cases occur in patients younger than 10 years of age and 60% of cases occur within the first two decades of life [1,2]. Pilomatricoma represents 0.12% of all skin tumors.[4]Its prevalence is poorly defined and its presentation varies and can simulate various other skin lesions also. Materials and Methods - This retrospective study was conducted to evaluate the clinical and histomorphology of pilomatricoma along with it’s incidence with respect to age, sex and site of lesion in a tertiary care hospital,Navi Mumbai . Following parameters were used to diagnose pilomatricoma 1.Shadow cells 2.Sebocytes 3.Matrical cells 4.Supramatrical cells 5.Isthmic differentiation 6.Infundibular differentiation 7.Calcification 8.Melanocytes 9.Basaloid epidermal proliferation 10.Trichohyaline granules 11.Outer sheath differentiation(clear cells) 12.Foreign body giant cells Results – A female preponderance with maximum cases in the 31 – 45 years age group was found in our study. The predominant site of lesion was head more specifically scalp followed by upper arm. The clinical diagnosis comprised of spectrum of lesions including dermoid cyst, sebaceous cyst ,unidentified lesion and inflammatory lymph node. Histological features of basaloid cells with eosinophillic ghost cells was found in almost all cases along with associated features of calcification and presence of giant cells. Conclusion – Pilomatricoma is not rare in occurrence but rarely diagnosed because of lack of confirmation of excised swelling. These are often mistaken for small round blue cell tumours in children, or for merkel cell carcinoma, basolioma and metastatic small cell carcinoma in adults, with possible aggressive therapeutic approach and hence, it is imperative that it should be kept in the differential diagnoses of all superficial skin tumors by dermatologists and surgeons. This study also helped in finding the prevalence of this disease in India, as there is paucity of the same in our country. Thus overall, this study helped in finding the various histomorphological features which are diagnostic of pilomatricoma . It also adds to the data of the disease in our country and will help in better clinical management as well as triage of patients.
"Calcifying Epithelioma of Malharbe - Pilomatricoma - A Retrospective Study in a Tertiary Care Hospital", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.6, Issue 12, page no.1 - 6, December-2021, Available :https://ijsdr.org/papers/IJSDR2112001.pdf
Volume 6
Issue 12,
December-2021
Pages : 1 - 6
Paper Reg. ID: IJSDR_193733
Published Paper Id: IJSDR2112001
Downloads: 000347381
Research Area: Biological Science
Country: navi mumbai, maharashtra, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
