INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
This is a novel study that demonstrated that salicylic acid can be formed into nanoemulsions for the treatment of Impetigo. The nanoemulsion area was raised using a pseudo ternary phase diagram, and the oil, surfactant, co-surfactant ratio was elevated. By using the spontaneous self emulsified approach, an optimized salicylic acid-loaded nanoemulsion was effectively generated and characterized for viscosity, droplet size, and transmission electron microscopy (TEM). The optimized nanoemulsion was then mixed with Polyethylene glycol to create a nanoemulsion that would make it easier to apply for the medicine superficially. Particle size in the produced nanoemulsion range from 100nm to 500nm. In vitro for up to 12 hours, medication relief was investigated. Further compatibility experiments were carried out to validate any drug-polymer interaction, and it was observed that there were no distinctive peaks, indicating that there is no substantial drug-polymer interaction. The formulation had a release rate of 51.22 percent in about 12 hours. The release studies of the improved formulations. Our study demonstrated that salicylic acid can be formed into nanoemulsions for topical use in the treatment of Impetigo.
Keywords:
Salicylic acid, Nanoemulsion, TEM, Droplet size analysis, FTIR
Cite Article:
"NANOEMULSION: A POTENTIAL FORMULATION OF IMPETIGO", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.6, Issue 10, page no.42 - 46, October-2021, Available :http://www.ijsdr.org/papers/IJSDR2110006.pdf
Downloads:
000337073
Publication Details:
Published Paper ID: IJSDR2110006
Registration ID:193572
Published In: Volume 6 Issue 10, October-2021
DOI (Digital Object Identifier):
Page No: 42 - 46
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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