INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Synthesis, characterization, and antimicrobial activity of 2-{4-(1H benzimidazole-2-yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde and its Cu (II) metal complex
The synthesis of 2-{4-(1H Benzimidazole-2yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde with Cu (II) metal complex was achieve. A 4-(1H Benzimidazole-2yl) aniline is synthesized by equimolar quantities of o-phenylenediamine and p-aminobenzoic acid with absolute alcohol. This further treated with 2-hydroxyl-4-methoxy benzaldehyde to form 2-{4-(1H Benzimidazole-2yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde. A Cu (II) metal complex was prepared by dissolving equimolar quantities of metal salt and Schiff base ligand in ethanol. All target compounds were characterized by M.P., TLC, UV-Visible and NMR and tested for antimicrobial activity in sterile saline by agar disk diffusion method against Escherichia Coli, Staphylococcus aureus and Candida albicans. All synthesized compound has shown good to moderate antimicrobial activity.
Keywords:
2-{4-(1H benzoimidazole-2-yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde; Copper; Antimicrobial; Metal complex; Schiff base
Cite Article:
"Synthesis, characterization, and antimicrobial activity of 2-{4-(1H benzimidazole-2-yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde and its Cu (II) metal complex", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.5, Issue 5, page no.459 - 463, May-2020, Available :http://www.ijsdr.org/papers/IJSDR2005072.pdf
Downloads:
000336256
Publication Details:
Published Paper ID: IJSDR2005072
Registration ID:191807
Published In: Volume 5 Issue 5, May-2020
DOI (Digital Object Identifier):
Page No: 459 - 463
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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