Synthesis, characterization, and antimicrobial activity of 2-{4-(1H benzimidazole-2-yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde and its Cu (II) metal complex

Ratnamala P. Sonawane , Ritima Singh , Atul Singh , Nilesh Kshirsagar

2-{4-(1H benzoimidazole-2-yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde; Copper; Antimicrobial; Metal complex; Schiff base

The synthesis of 2-{4-(1H Benzimidazole-2yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde with Cu (II) metal complex was achieve. A 4-(1H Benzimidazole-2yl) aniline is synthesized by equimolar quantities of o-phenylenediamine and p-aminobenzoic acid with absolute alcohol. This further treated with 2-hydroxyl-4-methoxy benzaldehyde to form 2-{4-(1H Benzimidazole-2yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde. A Cu (II) metal complex was prepared by dissolving equimolar quantities of metal salt and Schiff base ligand in ethanol. All target compounds were characterized by M.P., TLC, UV-Visible and NMR and tested for antimicrobial activity in sterile saline by agar disk diffusion method against Escherichia Coli, Staphylococcus aureus and Candida albicans. All synthesized compound has shown good to moderate antimicrobial activity.

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"Synthesis, characterization, and antimicrobial activity of 2-{4-(1H benzimidazole-2-yl) phenyl imino}-2-hydroxy-4-methoxy benzaldehyde and its Cu (II) metal complex", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.5, Issue 5, page no.459 - 463, May-2020, Available :https://ijsdr.org/papers/IJSDR2005072.pdf

Volume 5 Issue 5, May-2020

Pages : 459 - 463

Paper Reg. ID: IJSDR_191807

Published Paper Id: IJSDR2005072

Downloads: 000347201

Research Area: Chemistry

Country: Mumbai, Maharashtra, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2005072

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2005072

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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