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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Paper Title: Anticancer Properties of Silver nanoparticles
Authors Name: R.Kalai Selvi Ravishankar , Dr.Lakshmi
Unique Id: IJSDR2002039
Published In: Volume 5 Issue 2, February-2020
Abstract: In recent years, there has been escalating interest in the biomedical applications of nanoparticles (NPs). In particular, silver nanoparticles (AgNPs) are increasingly being investigated as tools for novel cancer therapeutics, capitalizing on their unique properties to enhance potential therapeutic efficacy. However, questions as to are we able to contain or control the toxicity effects of AgNPs, and how much do we know about the toxicological profile of AgNPs which are commonly used in emerging nanotechnology-based applications, still remain. Hence, serious considerations have to be given to the hazards and risks of toxicity associated with the use of AgNPs. This review focuses on the current applications of AgNPs, their known effects and toxicity, as well as the potential of harnessing them for use in cancer therapy.In the present review silver nanoparticles (AgNPs) due to their superior physicochemical, and biological properties are intensively dealt with. The proper knowledge of these characteristics is essential to maximize their potential applications in many areas while minimizing their hazards to humans and the environment. Nanotechnology is a most promising field for generating new applications in medicine. However, only few nanoproducts are currently in use for medical purposes. A most prominent nanoproduct is nanosilver. Nanosilver particles are generally smaller than 100nm and contain 20-15,000 silver atoms. At nanoscale, silver exhibits remarkably unusual physical, chemical and biological properties. Due to its strong antibacterial activity, nanosilver coatings are used on various textiles but as well as coatings on certain implants. Further, nanosilver is used for treatment of wounds and burns or as a contraceptive and marketed as a water disinfectant and room spray. Thus, use of nanosilver is becoming more and more widespread in medicine and related applications and due to increasing exposure toxicological and environmental issues need to be raised. In sharp contrast to the attention paid to new applications of nanosilver, few studies provide only scant insights into the interaction of nanosilver particle with the human body after entering via different portals. Biodistribution, organ accumulation, degradation, possible adverse effects and toxicity are only slowly recognized and this review is focusing on major questions associated with the increased medical use of nanosilver and related nanomaterials.. This manuscript aims to critically review AgNPs synthesized via different approaches, its utilization in cancer treatment and future challenges.
Keywords: Silver nanoparticles, antibacterial , anticancer , Medical application, treatment of cancer.
Cite Article: "Anticancer Properties of Silver nanoparticles", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.5, Issue 2, page no.237 - 240, February-2020, Available :http://www.ijsdr.org/papers/IJSDR2002039.pdf
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Publication Details: Published Paper ID: IJSDR2002039
Registration ID:191282
Published In: Volume 5 Issue 2, February-2020
DOI (Digital Object Identifier):
Page No: 237 - 240
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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