Comprehensive Review: Understanding and Addressing Dementia from Pathophysiology to Global perspectives

Srinidhi R , Malligeshwaran .N , Lokesh .B , Vignesh .M , Mohamed Shalim Khan .M

Dementia, Pathophysiology, Interventions, Ethical considerations, Global perspectives

Dementia is a complex neurodegenerative disorder characterized by cognitive decline, impacting millions of individuals worldwide. This comprehensive review delves into various aspects of dementia, including its pathophysiology, pharmacological and non-pharmacological interventions, caregiver support, ethical considerations, and global perspectives. The pathophysiology of dementia involves intricate mechanisms such as amyloid-beta accumulation, tau hyperphosphorylation, alpha-synuclein aggregation, vascular alterations, and frontotemporal lobar degeneration. While pharmacological interventions aim to alleviate symptoms, non-pharmacological approaches like cognitive stimulation therapy, physical exercise, music therapy, and reminiscence therapy offer promising avenues for enhancing quality of life. Ethical considerations in dementia care encompass autonomy, informed consent, end-of-life care, dignity preservation, and resource allocation. Addressing these ethical challenges requires person-centered approaches and ongoing dialogue among stakeholders. Global perspectives on dementia highlight epidemiological trends, cultural variations, healthcare systems, caregiver perspectives, and research innovations. Collaborative efforts are essential to tackle the multifaceted challenges posed by dementia and improve outcomes on a global scale. This review provides valuable insights into the current landscape of dementia research, treatment, and care, emphasizing the need for holistic approaches that prioritize individual well-being and dignity.

Published Paper   E-Certificate

"Comprehensive Review: Understanding and Addressing Dementia from Pathophysiology to Global perspectives", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 3, page no.674 - 679, March-2024, Available :https://ijsdr.org/papers/IJSDR2403098.pdf

Volume 9 Issue 3, March-2024

Pages : 674 - 679

Paper Reg. ID: IJSDR_210499

Published Paper Id: IJSDR2403098

Downloads: 000347081

Research Area: Health Science 

Country: Coimbatore, Tamil Nadu, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2403098

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2403098

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition