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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Comprehensive Review: Understanding and Addressing Dementia from Pathophysiology to Global perspectives |
| Authors Name: | Srinidhi R , Malligeshwaran .N , Lokesh .B , Vignesh .M , Mohamed Shalim Khan .M |
| Unique Id: | IJSDR2403098 |
| Published In: | Volume 9 Issue 3, March-2024 |
| Abstract: | Dementia is a complex neurodegenerative disorder characterized by cognitive decline, impacting millions of individuals worldwide. This comprehensive review delves into various aspects of dementia, including its pathophysiology, pharmacological and non-pharmacological interventions, caregiver support, ethical considerations, and global perspectives. The pathophysiology of dementia involves intricate mechanisms such as amyloid-beta accumulation, tau hyperphosphorylation, alpha-synuclein aggregation, vascular alterations, and frontotemporal lobar degeneration. While pharmacological interventions aim to alleviate symptoms, non-pharmacological approaches like cognitive stimulation therapy, physical exercise, music therapy, and reminiscence therapy offer promising avenues for enhancing quality of life. Ethical considerations in dementia care encompass autonomy, informed consent, end-of-life care, dignity preservation, and resource allocation. Addressing these ethical challenges requires person-centered approaches and ongoing dialogue among stakeholders. Global perspectives on dementia highlight epidemiological trends, cultural variations, healthcare systems, caregiver perspectives, and research innovations. Collaborative efforts are essential to tackle the multifaceted challenges posed by dementia and improve outcomes on a global scale. This review provides valuable insights into the current landscape of dementia research, treatment, and care, emphasizing the need for holistic approaches that prioritize individual well-being and dignity. |
| Keywords: | Dementia, Pathophysiology, Interventions, Ethical considerations, Global perspectives |
| Cite Article: | "Comprehensive Review: Understanding and Addressing Dementia from Pathophysiology to Global perspectives", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 3, page no.674 - 679, March-2024, Available :http://www.ijsdr.org/papers/IJSDR2403098.pdf |
| Downloads: | 000337363 |
| Publication Details: | Published Paper ID: IJSDR2403098 Registration ID:210499 Published In: Volume 9 Issue 3, March-2024 DOI (Digital Object Identifier): Page No: 674 - 679 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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