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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH
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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Volume 9 | Issue 5

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Paper Title:	Ameliorative Effect Of Vitamin C On Sodium Arsenate Induced Changes Of Blood Indices In Experimental Albino Mice
Authors Name:	G. VIJAYA , T. YAMINI , V. JAMEELA , G. MEENA KUMARI , K. NAGARAJU
Unique Id:	IJSDR2403023
Published In:	Volume 9 Issue 3, March-2024
Abstract:	It is well known that Sodium arsenate is necessary for the bone health, but ingestion of Sodium arsenate (NaAs) beyond the permissible limits is toxic to the animals. In the present investigation the author studied the ameliorative effect of vitamin C (Vit-C), on selected haematological parameters in NaAs intoxicated mice. 1/10th of LD50 of NaAs (i.e. 4.2mg/kg/bw) was orally administered for 28 days to mice to induce toxicity. In the next group vitamin C (i.e. 200mg/kg/day) was administered prior to 30 min of NaAs to see the ameliorating effect. Under NaAs toxicity the total RBC, Hb, WBC, PCV, MCV, MCH and MCHC were reduced. When vitamin C was co-administered with NaAs the haematological parameters did not show any significant change as compared to control indicating that vitamin C acts as an ameliorant against NaAs induced toxicity. The results are discussed in the light of available literature.
Keywords:	Sodium Arsenate, Vitamin C, Albino Mice , Haematalogical Parameters
Cite Article:	"Ameliorative Effect Of Vitamin C On Sodium Arsenate Induced Changes Of Blood Indices In Experimental Albino Mice", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 3, page no.142 - 148, March-2024, Available :http://www.ijsdr.org/papers/IJSDR2403023.pdf
Downloads:	000337362
Publication Details:	Published Paper ID: IJSDR2403023 Registration ID:210301 Published In: Volume 9 Issue 3, March-2024 DOI (Digital Object Identifier): Page No: 142 - 148 Publisher: IJSDR \| www.ijsdr.org ISSN Number: 2455-2631

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