Ameliorative Effect Of Vitamin C On Sodium Arsenate Induced Changes Of Blood Indices In Experimental Albino Mice

G. VIJAYA , T. YAMINI , V. JAMEELA , G. MEENA KUMARI , K. NAGARAJU

Sodium Arsenate, Vitamin C, Albino Mice , Haematalogical Parameters

It is well known that Sodium arsenate is necessary for the bone health, but ingestion of Sodium arsenate (NaAs) beyond the permissible limits is toxic to the animals. In the present investigation the author studied the ameliorative effect of vitamin C (Vit-C), on selected haematological parameters in NaAs intoxicated mice. 1/10th of LD50 of NaAs (i.e. 4.2mg/kg/bw) was orally administered for 28 days to mice to induce toxicity. In the next group vitamin C (i.e. 200mg/kg/day) was administered prior to 30 min of NaAs to see the ameliorating effect. Under NaAs toxicity the total RBC, Hb, WBC, PCV, MCV, MCH and MCHC were reduced. When vitamin C was co-administered with NaAs the haematological parameters did not show any significant change as compared to control indicating that vitamin C acts as an ameliorant against NaAs induced toxicity. The results are discussed in the light of available literature.

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"Ameliorative Effect Of Vitamin C On Sodium Arsenate Induced Changes Of Blood Indices In Experimental Albino Mice", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 3, page no.142 - 148, March-2024, Available :https://ijsdr.org/papers/IJSDR2403023.pdf

Volume 9 Issue 3, March-2024

Pages : 142 - 148

Paper Reg. ID: IJSDR_210301

Published Paper Id: IJSDR2403023

Downloads: 000347075

Research Area: Life Sciences 

Country: CHITTOOR, ANDHRA PRADESH, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2403023

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2403023

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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