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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | A Multi-centre study: Chest radiographic findings in adult patients with HIV/PTB co-infection and their CD4+ count |
| Authors Name: | Nwosu, Chinekwu Skye , Uzukwu, Ifeanyi Olisa , Eze, Kenneth .C. , Azubiuke, Chinedu .G. , Obi-Nwosu, Amaka Lovelyn |
| Unique Id: | IJSDR2307025 |
| Published In: | Volume 8 Issue 7, July-2023 |
| Abstract: | A MULTI-CENTRE STUDY: CHEST RADIOGRAPHIC FINDINGS IN ADULT PATIENTS WITH HIV/PTB CO-INFECTION AND THEIR CD4 COUNT. Uzukwu IO, Nwosu, CS, Eze KC, Azubuike CG, Emegoakor AC, Okorie AP, Obi-Nwosu AL, Uke KC ABSTRACT INTRODUCTION Tuberculosis (PTB) is a major global health problem, one-fourth of the world’s population is infected with the disease. The radiographic findings are atypical in the immuno-compromised and it resembles the primary type. AIM To determine the relationship between Chest radiographic findings of patients diagnosed with HIV/PTB co-infection and their CD4+ count. METHODS A cross-sectional, descriptive plain chest radiographic evaluation of pulmonary tuberculosis in patients with HIV/AIDS and their CD4+ count levels. RESULTS Nineteen subjects with HIV/PTB co-infection showed normal chest X-ray findings (CXR) . More females with CD4+ count < 200/mms3 (44 versus 33 for male to female values) while CD4+ count of > 200/mm3 showed more males (20 versus 15 for male to female values). Lobar pneumonia, miliary, cystic changes, fibrosis, and effusion were seen more in HIV/PTB subjects with CD4+ count < 200/mm3 with p- values of < 0.001, 0.016, 0.10, 0.003, and 0.016 respectively. Atypical CXR findings were seen in more subjects with a CD4+ count of <200mm3 (35) versus a CD4+ count of > 200mm3 (2) with a p-value of 0.001. The typical CXR findings were seen more in subjects with CD4+ counts of > 200/mm3 (27) versus those with CD4+ counts of < 200mm3 (9). CONCLUSION Patients with HIV/PTB co-infection have a significant chance of manifesting atypical CXR findings than typical CXR findings. KEYWORDS: CXR findings, CD4+ count, HIV/PTB co-infection, male-to-female values, radiographic. |
| Keywords: | CD4+ count, HIV/PTB co-infection, tuberculosis |
| Cite Article: | "A Multi-centre study: Chest radiographic findings in adult patients with HIV/PTB co-infection and their CD4+ count", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 7, page no.178 - 187, July-2023, Available :http://www.ijsdr.org/papers/IJSDR2307025.pdf |
| Downloads: | 000338536 |
| Publication Details: | Published Paper ID: IJSDR2307025 Registration ID:207594 Published In: Volume 8 Issue 7, July-2023 DOI (Digital Object Identifier): Page No: 178 - 187 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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