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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | DELETERIOUS EFFECT OF IONIZING RADIATION AND LEAD ON BLOOD OF SWISS ABLINO MICE . THIS PROTECTED BY EMBLICA OFFICINALIS. (LINN) |
| Authors Name: | DR. K.K. NAYAK , DR. A. CHAKRAWARTI , DR. R.K. PUROHIT |
| Unique Id: | IJSDR2306117 |
| Published In: | Volume 8 Issue 6, June-2023 |
| Abstract: | The extensive use of ionizing radiation recent in various branches of natural economy, medicine, Physiology and science- Technology has made radiation injury on urgent problem attracting the attention not only of specialists in a variety of clinical disciplines but also of a vast army of theoretical scientists. The heavy metals such as Lead entre in human body via food chain and cosmetics. Various public health measures have been undertaken to control, prevent and treat metal toxicity. Emblica is a natural herbs which have been proved to be patent enough to check the radiation and heavy metals induced histopatological histochemicall, biochemical and Hematological levels in swiss albino mice. the recent study will shed light upon the modulatory influence of Emblica against the deleterious effects induced by simultaneous exposure of radiation and heavy metal in the blood of Swiss albino mice. Here , six to eight week old male swiss albino mice were selected and divided in to seven group: Group I (Sham. irradiated), Group II (Treated with Lead acetate 20 ppm), Group III (Irradiated with 3.0 Gy and 6.0 Gy gamma rays) Group IV (Irradiated and Lead acetate treated), Group V (Lead acetate and Emblica treated), Group VI (radiation and Emblica treated) Group VII (radiation and Lead acetate and Emblic) were scarified at each post treatment intervals of 1,2,4,7,14 and 28 days. The blood, was taken out quantitatively analyzed for different biochemical parameters. Value of blood cells and Hb were found to decrease in all groups as compared to normal group and Biochemical value of M.CV, PCV, SGOT/AST and SGPT/ALT were also found. to decrease and combined treatment of radiation and Lead acetate synergistic effects were observed but Emblica treated animals exhibited less severe damage as compared to nondrug treated animals at all. the corresponding Intervals. Emblica reduced the severity of damage and made the recovery of biochemical Parameters. Therefore Emblica has reported as a good radioprotection in radiotherapy during clinical application of human beings. Keywords: Mice, Blood, Radiation, Lead, Emblica . |
| Keywords: | : Mice, Blood, Radiation, Lead, Emblica |
| Cite Article: | "DELETERIOUS EFFECT OF IONIZING RADIATION AND LEAD ON BLOOD OF SWISS ABLINO MICE . THIS PROTECTED BY EMBLICA OFFICINALIS. (LINN)", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 6, page no.802 - 810, June-2023, Available :http://www.ijsdr.org/papers/IJSDR2306117.pdf |
| Downloads: | 000337353 |
| Publication Details: | Published Paper ID: IJSDR2306117 Registration ID:207214 Published In: Volume 8 Issue 6, June-2023 DOI (Digital Object Identifier): Page No: 802 - 810 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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