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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | An overview of the cutting-edge Ocular in-situ Gel method for treating bacterial infections. |
| Authors Name: | Manichandra Das , Jyotirmoy Bondyopadhyay |
| Unique Id: | IJSDR2304420 |
| Published In: | Volume 8 Issue 4, April-2023 |
| Abstract: | Ocular delivery system is a challenging drug delivery system. Various types of conventional ocular therapies are present in our market for treating various types of bacterial infections. But these ocular therapies have many drawbacks, like drainage of the instilled solutions, lacrimation, tear turn over, tear evaporation, metabolism, limited corneal area binding by the lacrimal proteins, haziness of eyes etc. These problems can be overcome by using ocular In-situ gel formulation which is sol to gel conversion due to temperature change, pH change and ion activated systems. Various polymers (temperature sensitive, pH sensitive & ion sensitive polymers) are used to form in-situ gel formulation. This novel formulation promotes easy and convenience administration, deliver at the proper dose as well as prolong residence time. |
| Keywords: | Ocular, In-situ, Polymer, Temperature, pH, Ion. |
| Cite Article: | "An overview of the cutting-edge Ocular in-situ Gel method for treating bacterial infections.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.2704 - 2706, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304420.pdf |
| Downloads: | 000337348 |
| Publication Details: | Published Paper ID: IJSDR2304420 Registration ID:205962 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.36198 Page No: 2704 - 2706 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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