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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Efficacy of Carboxymethylcellulose 1% vs Rebamipide 2% in Dry eye disease [DED]: a comparative study |
| Authors Name: | Dr.Bhagyashree Satish Dhage , Dr.Valay Parekh , Dr.Roopa Naik , Dr.Madhurika Kalbande |
| Unique Id: | IJSDR2304072 |
| Published In: | Volume 8 Issue 4, April-2023 |
| Abstract: | Dry eye disease [DED] is an ocular film disease impacting millions of people globally. It is characterised by an unstable tear film leading to symptoms such as eye irritation, redness, foreign body sensation, photophobia and blurring of vision. This comparative study aims to evaluate the efficacy of Carboxymethylcellulose (CMC) 1% versus Rebamipide 2% eye drops in the management of dry eye disease (DED). It was a single-blinded prospective comparative study A total of 100 DED patients were enrolled in the study, and after randomisation, they received either CMC 1% or Rebamipide 2% eye drops. The patients were instructed to instil one drop in each eye four times a day for 12 weeks. Follow-up visits were scheduled at four and twelve weeks, during which tear film function and tear secretion tests were performed. The results indicated that both CMC 1% and Rebamipide 2% were effective in improving symptoms of DED. The rebamipide group gave better results at the end of 12 weeks in the improvement of multiple evaluating criteria as compared to the CMC group. Both drugs decreased the severity of dry eye disease. Also, the efficacy of rebamipide has been found to be better than carboxymethyl cellulose. This study suggests that both CMC 1% and Rebamipide 2% may be useful in the management of DED. |
| Keywords: | Dry eye disease Rebamipide CMC |
| Cite Article: | "Efficacy of Carboxymethylcellulose 1% vs Rebamipide 2% in Dry eye disease [DED]: a comparative study", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.382 - 388, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304072.pdf |
| Downloads: | 000337366 |
| Publication Details: | Published Paper ID: IJSDR2304072 Registration ID:204890 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): Page No: 382 - 388 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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