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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Comparative evaluation of intranasal, buccal and oral midazolam for procedural sedation in pediatric dental patients |
| Authors Name: | Dr. Malika Agarwal , Dr. Neerja Singh , Dr. Bibhav Dubey |
| Unique Id: | IJSDR2302104 |
| Published In: | Volume 8 Issue 2, February-2023 |
| Abstract: | Objectives: The objective of this study was to evaluate the safety and efficacy of Midazolam administered through intranasal, buccal and oral routes for procedural sedation in pediatric dental patients. Study Design: 90 children aged 3-11 years with Frankel behavior rating I and II were randomly divided into three groups for Midazolam administration through different routes (intranasal and buccal 0.3mg/kg, oral 0.5mg/kg respectively). During sedation session, children were evaluated for behavior response. Acceptance of drug, onset of sedation, peak sedation time, level of sedation, ease of treatment completion, recovery time, discharge time and post-operative complications were evaluated. Results: Both oral and intranasal routes produced minimal to moderate level of sedation. Intranasal route showed rapid onset time, early peak sedation time and better level of sedation. Buccal midazolam was not found to be effective and provided only minimal sedation in some patients. Oral and buccal groups exhibited better acceptance of drug. No post operative complications were found with any of these three routes. Faster recovery and discharge time with intranasal and buccal routes were found in comparison to oral group. Conclusions: Midazolam in the dose of 0.3mg/kg for intranasal route and 0.5 mg/kg for oral route was found to be effective but 0.3 mg/kg for buccal route was not found to be effective. All three routes were safe, none of them reported any intraoperative and postoperative complications. |
| Keywords: | Midazolam, Procedural sedation, Intranasal, Buccal, Oral |
| Cite Article: | "Comparative evaluation of intranasal, buccal and oral midazolam for procedural sedation in pediatric dental patients", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 2, page no.597 - 601, February-2023, Available :http://www.ijsdr.org/papers/IJSDR2302104.pdf |
| Downloads: | 000337349 |
| Publication Details: | Published Paper ID: IJSDR2302104 Registration ID:204041 Published In: Volume 8 Issue 2, February-2023 DOI (Digital Object Identifier): Page No: 597 - 601 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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