|
INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
Imp Links for Author
Imp Links for Reviewer
Research Area
Subscribe IJSDR
Visitor Counter
Copyright Infringement Claims
Indexing Partner
|
Published Paper Details
|
|
| Paper Title: | The next generation of oral reconstruction |
| Authors Name: | Dr Tavleen Kaur , Dr Shefali Singla , Dr Lalit Kumar |
| Unique Id: | IJSDR2210060 |
| Published In: | Volume 7 Issue 10, October-2022 |
| Abstract: | BACKGROUND: In prosthodontics, the replacement of teeth becomes difficult in case of large bony defects as a result of severe bone resorption, periodontal disease or trauma. Therefore, stem cell and tissue engineering therapies are expected to provide a new dimension to regenerate defects. This dimension has even extended to regeneration of salivary glands, tongue, craniofacial muscles and TMJ cartilage. SUMMARY: Stem cells considerations for dental application include adult mesenchymal cells and pluripotent stem cells. However, teeth and salivary glands which are epithelial-mesenchymal interaction products are difficult to derive from mesenchymal stem cells(MSCs) hence embryonal cells(ES) have been introduced which had the capability of organogenesis. Induced pluripotent stem cell(iPS) were later introduced that even had the capability to suppress the immune reaction. In Prosthodontics, stem cells in the form of bone grafts are being used widely to augment bone for implant placement. However with newer technology, and use of dental follicle stem cells, growth of the tooth is also possible which would help in oral rehabilitation. Literature also supports regenerative potential of stem cells for other hard andsoft tissues in oral cavity like tongue, condyle, salivary glands etc. There are concerns of biosafety for human trials but once unleashed, a new era of oral rehabilitation will be on its way. CONCLUSION: Current active research is focused on tissue engineering and chair side cellular grafting approaches. With the increasing advances and successful animal studies, stem cell regeneration can prove to be a new era in the field of prosthodontics and oral rehabilitation. |
| Keywords: | : Regenerative prosthodontics, Stem cells, biohybrid implant, Bioengineered tooth |
| Cite Article: | "The next generation of oral reconstruction", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 10, page no.343 - 348, October-2022, Available :http://www.ijsdr.org/papers/IJSDR2210060.pdf |
| Downloads: | 000337349 |
| Publication Details: | Published Paper ID: IJSDR2210060 Registration ID:201598 Published In: Volume 7 Issue 10, October-2022 DOI (Digital Object Identifier): Page No: 343 - 348 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijsdr.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
Track Paper
Important Links
Conference Proposal
ISSN
 |
 |
DOI (A digital object identifier)
  Providing A digital object identifier by DOI How to GET DOI and Hard Copy Related |
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
 |
 |
 |
Social Media
Indexing Partner |
|||
| Copyright © 2024 - All Rights Reserved - IJSDR | |||
Facebook Twitter Instagram LinkedIn