A NOVEL APPROACH: SUSTAINED/ CONTROLLED RELEASE DRUG DELIVERY SYSTEM
Arvind kumar
, Dr. Rajesh Asija , Anil Kumar Goyal , Yogesh Kumar garg , Nirupma Tomar
Basic rationale of sustained release drug delivery system optimizes the pharmacokinetic, biopharmaceutical, and pharmacodynamics properties of a drug in such a way that its utility is maximized, side-effects are reduced & cure of the disease is achieved. Sustained release dosage forms are designed to release a drug at a predetermined rate by maintaining a constant drug level for a specific period of time with minimum side effects. There are several advantages of sustained release technology over conventional dosage forms like improved patient compliance due to less frequent drug administration, maximum utilisation of the drug, reduction of fluctuation in steady-state drug levels, increased safety margin of potent drug, reduction in healthcare costs through improved therapy and shorter treatment period. Drug release through matrix system is determined by Water penetration, Polymer swelling, Drug dissolution, Drug diffusion, Matrix erosion have been utilized as formulation approaches. The main goal in designing sustained release delivery systems is to reduce frequency of dosing or to increase effectiveness of the drug by localization at the site of the action, reducing dose required or providing uniform drug delivery.
"A NOVEL APPROACH: SUSTAINED/ CONTROLLED RELEASE DRUG DELIVERY SYSTEM", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 9, page no.341 - 345, September-2022, Available :https://ijsdr.org/papers/IJSDR2209053.pdf
Volume 7
Issue 9,
September-2022
Pages : 341 - 345
Paper Reg. ID: IJSDR_201586
Published Paper Id: IJSDR2209053
Downloads: 000347215
Research Area: Pharmacy
Country: Bharatpur, Rajasthan, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave