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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | EVALUATION OF ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF LOTION CONTAINING ALOE VERA, NEEM EXTRACT AND GARLIC OIL |
| Authors Name: | SUBHASHITHA S , ANSHIYA , POOJARI TRUPTI , FATHIMA WAFIYA , RAVI KUMAR |
| Unique Id: | IJSDR2208076 |
| Published In: | Volume 7 Issue 8, August-2022 |
| Abstract: | The aim of this study to develop a topical lotion formulation of herbal extract containing garlic oil, aloe vera and Neem extract with different concentration of polymer. Topical lotion formulation was designed using Stearic acid and triethanolamine with different ratio were chosen as independent variables while pH and viscosity as dependent factors. The lotion was prepared by adding non-polar phase to polar phase with rapid stirring to avoid separation of water and oil phase. Non-polar phase was first melted together and slowly added to the preheated mixture of polar phase. Stearyl alcohol in combination with other ingredients in the formulation such as triethanolamine and stearic acid forms an emulsion. Three different types of formulation oil in water (o/w) ointment namely F1,F2, F3& F4 where formulated by using different Herbal extract, concentration of polymer and propylene glycol solvent. The prepared lotion was evaluated for different parameter such as organoleptic properties, pH, practical yield, irritancy, washability and phase separation etc. The evaluation for Antibacterial and Antifungal activity was done using cup plate method. The lotion showed promising Antibacterial and Antifungal activity against other strains used for the study. The lotion was stable at room temperature. The formulation showed no redness, edema, inflammation and irritation that indicated that it is safe to use Then the F3 and F4 formulation showed better consistency and spreadability when compared to F1 and F2 formulation. |
| Keywords: | Aloe vera, Azadirachta indica, Garlic oil, Antifungal, Anti bacterial and Lotion |
| Cite Article: | "EVALUATION OF ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF LOTION CONTAINING ALOE VERA, NEEM EXTRACT AND GARLIC OIL", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 8, page no.547 - 549, August-2022, Available :http://www.ijsdr.org/papers/IJSDR2208076.pdf |
| Downloads: | 000337348 |
| Publication Details: | Published Paper ID: IJSDR2208076 Registration ID:201204 Published In: Volume 7 Issue 8, August-2022 DOI (Digital Object Identifier): Page No: 547 - 549 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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