INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Life Cycle Management of Analytical RP-HPLC Method Development for Assay of Rizatriptan in Immediate Release Dosage Form
Authors Name:
Mr. Avinash M. Bhagwat
, Dr. Rahul V. Mayee , Dr. Ajit B. Ekal
Unique Id:
IJSDR2207056
Published In:
Volume 7 Issue 7, July-2022
Abstract:
In this research work of life cycle management of analytical RP-HPLC method development for assay of Rizatriptan in immediate release dosage form, the RP-HPLC assay method was developed and validated for Rizatriptan. Stress study is also carried out. The chromatographic conditions will be as, Symmetry C-18, 150 mm x 4.6 mm, 5 mm column at 30°C temperature by using a mobile phase [Mixture of 100 mL Acetonitrile, and 900 mL Buffer solution] at a flow rate of 1.8mL/min, and UV detection at 225 nm and run time is 15 min. This life cycle management stability indicating RP-HPLC analytical method is economical, specific, accurate, precise and robust for assay of Rizatriptan in immediate release dosage form.
Keywords:
Rizatriptan, Life Cycle Management, RP-HPLC Method Development, Validation, Immediate Release Dosage Form
Cite Article:
"Life Cycle Management of Analytical RP-HPLC Method Development for Assay of Rizatriptan in Immediate Release Dosage Form", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 7, page no.402 - 412, July-2022, Available :http://www.ijsdr.org/papers/IJSDR2207056.pdf
Downloads:
000337214
Publication Details:
Published Paper ID: IJSDR2207056
Registration ID:200935
Published In: Volume 7 Issue 7, July-2022
DOI (Digital Object Identifier):
Page No: 402 - 412
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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